Endocrine Lecture Flashcards

1
Q

Describe the difference between endocrine and exocrine glands?

A

endocrine: do not have a duct to the surface of the skin or lumen of organ (except goblet cells) and secrete hormones to the blood stream
exocrine: have ducts to the surface

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2
Q

Exocrine and endocrine function of the pancreas

A

exocrine: pancreatic juices
endocrine: insulin and glucagon production

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3
Q

Exocrine and endocrine function of the testes

A

exocrine: sperm
endocrine: testosterone

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4
Q

Exocrine and endocrine function of the ovaries

A

exocrine: ova
endocrine: estrogen and progesterone

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5
Q

which type of hormone is water soluble?

A

amino-acid based hormones

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6
Q

which type of hormone is lipid soluble?

A

steroid hormones

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7
Q

What are three examples of amino acid based hormones

A

amines, peptides, and proteins

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8
Q

what are two examples of steroid hormones

A

gonadal and adrenocortical hormones

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9
Q

What are steroid hormones made from?

A

cholesterol

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10
Q

How do intracellular hormone receptors work?

A

Lipid soluble hormones + thyroid hormones enter the cell and bind to intracellular receptor and form hormone-receptor complex. Complex binds to DNA which starts transcription of target gene to create protein that alters cell activity

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11
Q

how do cell membrane receptors work?

A

-Water soluble hormone binds to receptor and activates G protein
-G protein activates adenlyl cyclase
-adenlyl cyclase catalyzes the conversion of ATP to cAMP.
-cAMP activates protein kinases
-protein hydrolyzes ATP to ADP
-free phosphate phosphorylates proteins, activating them
-proteins change cellular activity

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12
Q

what is the first messenger in the membrane receptor cascade?

A

the hormone

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13
Q

what is the second messenger in the membrane receptor cascade?

A

cyclic AMP (cAMP)

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14
Q

How are hormone levels regulated in the blood?

A

negative feedback

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15
Q

What are the three stimuli that stimulate hormone release?

A

humoral, neural, and hormonal

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16
Q

define humoral stimuli

A

extracellular concentration of solutes, too high or low

17
Q

define neural stimuli

A

direct neural communication to glands

18
Q

define hormonal stimuli

A

gland stimulated by another hormone

19
Q

name for the anterior pituitary

A

adenohypophysis (glandular tissue)

20
Q

name for the posterior pituitary

A

neurohypophysis (axons and axon terminals of the neurons of the hypothalumus)

21
Q

what is the main function of the neurohypophysis

A

storing and secreting hormones made by the hypothalamus. released by action potentials

22
Q

What hormones are made by the supraoptic nucleus and the paraventricular nucleus of the hypothalamus?

A

supraoptic=antidiuretic hormone
paraventricular= oxytocin

23
Q

what method regulates oxytocin levels?

A

positive feedback