Understanding Cancer Flashcards

1
Q

Different kinds of cancer

A

-Carcinoma
-Sarcoma
-Lymphoma
-Leukemia

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2
Q

Carcinomas

A

-Most common type of cancer
-Arise from the cells that cover external and internal body surfaces
-Lung, breast, and colon are the most frequent cancers of this type in the U.S.

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3
Q

Sarcomas

A

-Cancers arising from cells found in the supporting tissues of the body
-Bones, cartilage, fat, connective tissue, and muscle

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4
Q

Lymphomas

A

-Arise in the lymph nodes and tissues of the body’s immune system

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5
Q

Leukemia

A

-Cancers of the immature blood cells that grow in bone marrow
-Tend to accumulate in large numbers in the blood stream

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6
Q

Clonal Proliferation

A

The tumor cells all contain the mutations that allowed them to undergo unchecked proliferation without cell cycle arrest or apoptosis

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7
Q

Invasion

A

Cancer cells grow into surrounding tissues and blood vessels

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8
Q

Metastasis

A

-Cancer cells are transported by the circulatory system to distant sites
-Cancer cells invade and grow at new location

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9
Q

Benign Tumor

A

-Not cancer
-Tumor cells grow only locally and cannot spread by invasion or metastasis

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10
Q

Malignant Tumor

A

-Cancer
-Cells invade neighboring tissues, enter blood vessels, and metastasize to different sites

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11
Q

Benign Characteristics

A

-Slow growth
-Well differentiated (cellular composition)
-Looks like original tissue
-Well defined capsule
-No metastais

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12
Q

Malignant Characteristics

A

-Rapid growth
-Frequent cell division/mitosis
-Poorly differentiated
-Not encapsulated
-Invades local tissues
-Spreads easily (blood and lymphatics)

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13
Q

How many stages of cancer metastasis?

A

Four

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14
Q

Stage 1

A

Cancer confined to organ of origin

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15
Q

Stage 2

A

Cancer is locally invasive

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16
Q

Stage 3

A

Cancer has spread to regional structures (lymph nodes)

17
Q

Stage 4

A

Cancer has spread to distant areas of the body

18
Q

Examining biopsy tissue

A

-Large number of irregularly shaped dividing cells
-Large, variably shaped nuclei
-Small cytoplasmic volume relative to nuclei
-Variation in cell size and shape
-Loss of normal specialized cell features
-Disorganized arrangement of cells
-Poorly defined tumor boundary

19
Q

Anaplasia

A

Loss of mature characteristics

20
Q

Autonomy

A

Loss of response to environmental signals