Session name & Code: [003] CAL: Principles of endocrine homeostasis

Question 1

Answer 1

Question 2

Answer 2

Question 3

Answer 3

Question 4

Answer 4

Question 5

Complete the following table by suggesting three possible identities for the hormone “X” and the corresponding identities of the regulated solute/ion “Y”

Answer 5

Question 6

Suggest three possible reasons why the homeostatic relationship between X and Y might fail:

Answer 6

Question 7

In general, how do hydrophobic hormones affect metabolism?

Answer 7

Question 8

Complete the following table by suggesting corresponding identities for the hormones “A”, “B” and “C” in three different endocrine axes (the hypothalamo-pituitary-testicular axis is give as an example):

Answer 8

Question 9

Suggest four possible reasons why the negative feedback between hormones “C” and “B” might fail:

Answer 9

Question 10

In the generalised endocrine axis shown on the previous page, assume that hormone “C” acts to increase the concentration of “S”. Explain what would happen to the concentration of the stimulatory hormone “A” and of the solute/ion “S” if a mutation in the receptor for hormone “C” were to render the patient resistant to the actions of this hormone?

Answer 10

Question 11

Give two examples of endocrine axes in which the phenomenon of positive feedback is normal and physiologically important:

Answer 11

Question 12

Answer 12

Question 13

-Which of the factors listed above (if any) is NOT relevant in determining the concentration of the steroid hormone, progesterone?

Answer 13