Module 2 Section 6 - The Cell Cycle and Mitosis Flashcards

1
Q

What is the cell cycle

A

The process that all body cells in multicellular organisms use to grow and divide

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2
Q

When does the cell cycle start

A

When a cell has been produced by cell division

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3
Q

When does the cell cycle end

A

It ends with the cell dividing to produce two identical cells

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4
Q

What does the cell cycle consist of

A

Interphase (Cell growth and DNA replication)
M Phase (Mitosis and cytokinesis)

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5
Q

Interphase is divided into 3 stages what are they

A

G1 (gap phase 1), S (synthesis), G2 (gap phase 2)

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6
Q

What happens in gap phase 1

A

In gap phase 1 the cell grows and new organelles and proteins are made

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7
Q

How is the cell cycle regulated

A

By checkpoints

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8
Q

When do checkpoints occur

A

At key points during the cycle to make sure it’s ok for the process to continue

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9
Q

What happens after g1

A

The cell undergoes checks at the g1 checkpoint

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10
Q

What does the g1 checkpoint check for

A

Checks that the chemicals needed for replication are present and checks for damage to the DNA before enter S-phase

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11
Q

After passing the g1 checkpoint what happens to a cell in the cell cycle

A

The cell enters synthesis phase

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12
Q

What happens in the synthesis phase in the cell cycle

A

The cell replicates it’s DNA ready to divide by mitosis

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13
Q

What happens to the cell after synthesis stage

A

It enters g2 (gap phase 2)

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14
Q

What happens in g2

A

Cell keeps growing and proteins needed for cell division are made

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15
Q

What happens after g2

A

The cell has to clear the g2 checkpoint

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16
Q

What does the g2 checkpoint check for

A

The cell checks whether all the DNA has been replicated without any damage

17
Q

What happens after the cell clears the g2 checkpoint

A

It enters m-phase

18
Q

What happens in m-phase

A

The cell goes through mitosis and cytokinesis

19
Q

What happens to the cell after m-phase

A

It has to pass through the metaphase checkpoint

20
Q

Where does interphase start

A

G1

21
Q

Where does interphase end

A

G2 checkpoint

22
Q

How many stages does mitosis have

A

4 stages

23
Q

Why is mitosis needed

A

Mitosis is needed for growth of multicellular organisms and for repairing damaged tissues

24
Q

What are the stages of mitosis in order

A

Prophase
Metaphase
Anaphase
Telophase

25
Q

What happens before mitosis

A

Interphase

26
Q

What happens to the cell in interphase

A

The cell prepares for division
The cell’s DNA will unravel and replicate to double its genetic content
Organelles are replicated so it has spare ones
ATP content is increased so it provides energy needed for cell division

27
Q

What happens to the cell in the prophase stage of mitosis

A

Chromosomes condense (get shorter and fatter)
Centrioles move to opposite ends of the cell
Network of protein fibres form, called the spindle
Nuclear envelope breaks down, DNA lies free in cytoplasm

28
Q

What happens to the cell in the metaphase stage of mitosis

A

The chromosomes (each with 2 Chromatids) line up along the middle of the cell
They attach to the spindle by their centromere

29
Q

What happens at the metaphase checkpoint

A

The cell checks that all the chromosomes are attached to the spindle before mitosis can continue

30
Q

What happens to the cell in the anaphase stage of mitosis

A

The centromere divide - each pair of sister chromatids are separated
The spindles contract pulling chromatids to the opposite ends of the cell, centromere first

31
Q

What happens to the cell in the telophase stage of mitosis

A

The chromatids reach the opposite poles on the spindle
They uncoil and become long and thin again - called chromosomes again
Nuclear envelope forms around each group of chromosomes, now 2 nuclei

32
Q

What happens in cytokinesis

A

The cytoplasm divides
In animal cells, cleavage furrow forms to divide the cell membrane
There are now two daughter cells (genetically identical to the original)

33
Q

When does cytokinesis start

A

Usually begins in anaphase

34
Q

When does cytokinesis end

A

Telophase

35
Q

As mitosis begins the chromosomes are made of what

A

2 separate strands called chromatids
1 centromere

36
Q

How can you observe the cell cycle

A

By staining chromosomes