Hepatic Encephalopathy Flashcards
Hepatic Encephalopathy
Synonyms
Porto systemic encephalopathy
Precipitating Factor for Hepatic Encephalopathy
⚡⚡ MOST COMMON Cause
⚡⚡ 2nd MOST COMMON Cause
⚡⚡ Reversible Cause
⚡⚡ MOST COMMON Cause
🎯 GI Bleeds (DUE TO: Varices)
⚡⚡ 2nd MOST COMMON Cause
🎯 Constipation (Patient’s urea get absorbed)
⚡⚡ Reversible Cause
🎯 Protein Rich Diet
🎯 INFECTION / SEPSIS
🎯 RENAL FAILURE
🎯 ELECTROLYTE ABNORMALITIES
✨ Hyponatremia
✨ Hypokalemia
✨ Metabolic Alkalosis
🎯 Dehydration
🎯 Drugs: Opiates
⚡⚡ MOST COMMON Toxin causing HEPATIC ENCEPHALOPATHY
Ammonia (NH3)
Cells affected in Hepatic Encephalopathy
Astrocytes
⬇️ develop into
Alzheimer’s Type 2 Astrocytes
Grading System used for a hepatic Encephalopathy
⚡⚡ MOST Accurate
- West Haven Grading
- FOUR (Full OUtline of Responsiveness)
⚡⚡ MOST Accurate
Pathogenesis of Hepatic Encephalopathy
Other toxins involved in Hepatic Encephalopathy
- Merceptans
- Phenols
- FFA
- GABA
- Octapamine
- Aromatic AA
- Manganese
Types of Hepatic Encephalopathy
🧠⚡ A for A, C for C⚡
⚡⚡ MOST COMMON Hepatic Encephalopathy
🧠⚡ Commomest⚡
Type C
Modified WEST HAVEN Criteria
NORMAL Serum Ammonia rules out
Hepatic Encephalopathy
New DIAGNOSTIC MARKER OF HEPATIC ENCEPHALOPATHY
3-Nitrotyrosine
Clinical test for DIAGNOSIS🚦 of HEPATIC ENCEPHALOPATHY
Constructional Apraxia Test (Reitan Number Connection Test)
TRIPHASIC WAVES IN EEG IN COMA Patient indicates
HEPATIC ENCEPHALOPATHY
💊💉 MANAGEMENT of HEPATIC ENCEPHALOPATHY
- Correct precipitating Factor
- Lactulose Bowel Wash
- Rifaximin Gut Sterilization
- Low Protein Diet
