Substance of Abuse Flashcards

1
Q

Other names for Ethanol

A

Grain alcohol
Spiritus vini rectificatus
Neutral spirit

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2
Q

Most widely abused recreational substance

A

Ethanol

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3
Q

Responsible for major medical and socioeconomic problems

A

Ethanol

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4
Q

Alcohol content of Beer

A

4-5%

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5
Q

Alcohol content of Wine

A

10-14%

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6
Q

Alcohol content of Distilled spirits

A

30-50%

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7
Q

Metabolites of Alcohol

A

Acetaldehyde, Acetic Acid

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8
Q

S/S of Alcohol Poisoning

A

CNS depression, Acid-base Imbalance,
Metabolic Acidosis, Impaired Thermal Regulation
Hypoglycemia, Coma, Tachycardia

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9
Q

Treatment of Acute Alcohol Toxicity

A

Supportive Care
Fluids and Electrolytes
Vit B1 (Thiamine)

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10
Q

Treatment of Chronic Alcohol Poisoning

A

Disulfiram - Aldehyde dehydrogenase Inh
Naltrexone, Acamprosate - Reduce cravings and Inc. Abstinence rate
Behavioral Therapy

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11
Q

Active Ingredient of Tobacco

A

Nicotine

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12
Q

Lethal dose of Nicotine

A

Adult: 40-60mg
Child: 1.5 - 2 mg/kg

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13
Q

Treatment of Nicotine Toxicity

A

Activated Charcoal
Gastric Lavage
Mecamylamine (Inversine®)

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14
Q

From Papaver Somniferum (opium poppy)

A

Opioids

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14
Q

Natural Opioids

A

Opium, Morphine

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15
Q

Semi-synthetic Opioid

A

Heroin (Diacetylmrphine)
Codeine (Methylmorphine)

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16
Q

Synthetic Opioids

A

Methadone & Meperidine (Pethidine)

17
Q

Opioid Toxicity Manifestations

A

Coma (LOC)
Miosis (pinpoint pupil)
Respiratory depression

18
Q

Meperidine may cause

A

Seizure

19
Q

Treatment for Opioids Toxicity

A

Naloxone
(pure Antagonist)
Naltrexone
Nalorphine
Nalmefen

20
Q

Hallucinogens

A
20
Q

Hallucinogens

A

Lysergic Acid Diethylamide (LSD)
Marijuana
Phencyclidine
Mescaline
Lysergic Acid Amide (LSA)

21
Q

Marijuana is derived from?

A

Cannabis sativa/sativum

22
Q

Other names for Marijuana

A

Mary Jane, Hashish, Indian Hemp, Weeds

23
Q

Most commonly used Illegal Drug

A

Marijuana

24
Q

Active constituent of Marijuana

A

△-9-tetrahydrocannabinol (THC)
Cannabidiol

25
Q

Angel Dust

A

Phencyclidine

26
Q

Dissociative anesthetic

A

Phencyclidine

27
Q

S/S of Phencyclidine Poisoning

A

Low: Bloodshot eyes, Loss of balance
Med: Anesthesia, HPN
High: Convulsion

28
Q

Tx of Phencyclidine poisoning

A

Benzodiazepine, Diazepam (for seizure)
Nitroprusside (for HPN)

29
Q

Mescaline is derived from

A

Peyote cactus (Lophophora williamsii)

30
Q

Mescaline Toxicity S/S

A

Sympathomimetic Toxidrome

31
Q

TF: LSD is an Ergot derivative

A

True

32
Q

Most potent hallucinogen

A

LSD

33
Q

LSA is derived from

A

Morning glory family (Ipomoea indica)

34
Q

Shabu

A

Methamphetamine

35
Q

Ecstasy

A

3, 4-methylenedioxy-N-methamphetamine, or MDMA

36
Q

S/S of Amphetamine poisoning

A

Seizures
Psychosis/Agitation
Hypertensive crisis
Arrhythmias

37
Q

Treatment for Amphetamine Poisoning

A

Seizures: Diazepam, Phenytoin
Psychosis/Agitation: Chlorpromazine, haloperidol, Diazepam
Hypertensive crisis: B-blockers, a-blockers
Arrhythmias: Propanolo, Lidocaine

38
Q

Cocaine is derived from

A

Erythroxylon coca

39
Q

Cocaine

A

Crack, Freebase

40
Q

Treatment of Cocaine Toxicity

A

Seizures: Benzodiazepine
Psychosis: Neuroleptics
HPN: Labetalol