GI Part 4- 1 Flashcards
What type of wall is the endothelial wall of the liver? It allows passage of large molecules, glucose and amino acids?
Fenestrated
What organ produces most of the body’s circulating plasma proteins?
Liver
What are lipoproteins classes categorized by?
Their density
What lipoprotein has the following characteristics?
Transport of triglycerides from the liver to adipose tissue/other organs
VLDLs
What lipoprotein has the following characteristics?
VLDLs remnants, after the FFA’s have been released
50% become VLDLs
50% become LDLs
IDLs
What lipoprotein has the following characteristics?
Transport of cholesterol esters from the liver to other tissues
Increases in people eating a diet hight in saturated fat, obese, and/or sedentary
LDLs
What lipoprotein has the following characteristics?
Remove cholesterol from the peripheral tissue and transport it to the liver
It is believed they can absorb cholesterol that are being deposited in the arteries
HDLs
What hormone in the liver is:
Prohormone
Angiotensinogen
What is the liver hormone:
Hormone growth factor
Thrombopoetin
What is the liver hormone:
Produced in response to growth hormone
IGF
What is the liver hormone:
Small peptide hormone for iron homeostasis
Hepcidin
What are the group of reaction in the conversion of toxic to non toxic, water soluble and more excretable substances?
Bio transformations
Since most drugs are liposoluble, what is essential for the termination of their action and their elimination from the body?
Bio transformation
What is the major site of drug biotransformation?
Liver
What does drug metabolism lead to an increase in?
Polarity
