GI Part 4- 3

Question 1

What are protein digestive enzymes (proteases) which are harmful to pancreatic cells released as? They also become active when they reach the doudenum?

Answer 1

Zymogens- inactive form

Question 2

What cells have receptors for ACh, CCK, and secretin?

Answer 2

Pancreatic cells

Question 3

What 2 GI hormones stimulate secretion of an enzyme and chloride-rich fluid?

Answer 3

ACh and CCK

Question 4

What GI hormone stimulates the production of a bicarbonate-rich secretion?

Answer 4

Secretin

Question 5

Increase in starch = _________ amylase

Answer 5

Increase

Question 6

Increase in fat and protein = _______ in lipases and peptidases

Answer 6

Increase

Question 7

What leads to maldigestion, greasy/oily stools, polyphagia, rapid weight loss?

Answer 7

Pancreatic insufficiency

Question 8

What leads to:
Acini destroyed and replaced by connective tissue because of auto digestion
Increased risk when eating too much fat, human food or garbage

Answer 8

Pancreatitis

Question 9

What 3 exocrine pancreas enzymes:
Cleave interior peptide bonds

Answer 9

Trypsinogen, chymotrypsinogen, proelastase

Question 10

What exocrine pancreas enzyme:
Release amino acids at C terminus

Answer 10

Procarboxypeptidase

Question 11

What exocrine pancreas enzyme:
Cleaves the ester bonds at the 1- and 3-positions, producing FFA and MAG?

Answer 11

Lipase

Question 12

What exocrine pancreas enzyme:
Cleaves the ester bonds at 2-positions of phospholipids

Answer 12

Phospholipase

Question 13

What exocrine pancreas enzyme:
Cleaves the starch and glycogen to maltose and glucose?

Answer 13

Amylase

Question 14

What exocrine pancreas enzyme:
Cleaves RNA to nucleotides

Answer 14

Ribonuclease

Question 15

What exocrine pancreas enzyme:
Cleaves DNA to nucleotides?

Answer 15

Deoxyribonuclease