5- Pathophysiology of traumatic brain injury Flashcards

1
Q

T/F Dogs & cats have a remarkable ability to compensate for loss of cerebral tissue

A

True

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2
Q

T/F perfusion decreases if the brain enlarges

A

True

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3
Q

How is secondary brain injury triggered

A

Is triggered by Excitatory neurotransmitters
By ROS (reactive oxygen species)
And Pro-inflammatory cytokines

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4
Q

Name 2 systemic contributions to secondary brain injury

A

Hypotension
hypoxia
hypo/hyperglycaemia
hypo/hypercapnia
hyperthermia

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5
Q

What makes up the initaial neurologic assessment

A

consciousness
breathing pattern
pupil size and responsiveness
ocular position and movements
skeletal motor responses

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6
Q

What is MGCS

A

modified glasgow coma scale- evaluates the neurological function
higher scores correlates with a better prognosis

Level of consciousness most reliable measure o impaired cerebral function

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7
Q

What does secondary brain injury lead to

A

cerebral oedema formation
increased intracranial pressure
compromised to the blood-brain barrier
alterations in cerebrovascular reactivity

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