Anthrax Flashcards
What are the clinical forms of anthrax in humans?
Skin
GI anthrax (mortality is 50%)
Inhalation anthrax
Meningitis antrax
Injection Al anthrax
What is a malignant pustule?
Painless lesion, painful lymph node
Oedema around the lesion
Face is usually accompanied by gangrene
What is GI anthrax? And pulm
Intake of contaminated meat
What is Bartonellosis?
Acute and chronic forms
Bartonella Bacilliformis
Where is Bartonella typically found?
Inter-Andean valleys in Peru
How many Bartonella species exist that cause disease in humans, what is most typical one?
11 species
Bartonella Henselae
What is the main reservoir for B henslae?
Cats-scratch or bite!
What is the presentation of cutaneous bartonella?
Non specific scratch/skin lesion
Painful lymphadenopathy
What is the best test for B Henslae?
Immunofluorescence blood test
What are the symptoms in acute phase of carrion disease?
Severe anaemia, pallor, fever, hepatomegaly, cardiac murmur and jaundice
What happens during the acute phase of carrion disease?
There is an acute decrease in immune system and so patients die from opportunistic infections
What are the cardiovascular complications?
Pericarditis, tamponade, heart failure, tachyarrhythmias
What are the neurological complications?
Seizures, coma
What do you see in the smears of bartonella?
Intra-erythrocytic gram negative coccobacilli, prolonged disease gett coccid forms in RBCs
Tx of chronic bartonella?
Azithromycin
