Eosinophilia

Question 1

What is eosinophilia defined as?

Answer 1

> 5-10% of WCC
450 or 500
Hypereosiniphilia is >1500

Question 2

Causes of Eosinophilia other than Helminths?

Answer 2

Bronchopulmonary aspergillosis
Coccidioidomycosis
Scabies, Myiasis
Cystoisospora, sarcocystis infections
Congenital toxoplasmosis
HIV (allergies, eosinophilic folliculitis)

Question 3

Helminths causes of eosinophilia?

Answer 3

Schistosomiasis, typically acute schisto
Strongyloides
Asacaris
Hookworm
Loa Loa

Echinococcus, Fasciola, Dracunculus, Enterobius,
Gnathostomiasis, Hymenolepis, Opisthorchis, Filaria

Question 4

When to think of Helminths in travellers with eosinophilias?

Answer 4

If been in Subsaharan Africa
More common in immigrants and expats
Think about Helminths if eosinophil >1500

Question 5

Name larva migrans syndromes

Answer 5

Toxocara Catti/Cani
Baylisascaris Procyonis
Angiostrongylus Cantonensis
Gnathostoma Spinigerum
Asacaris Lumbrocoides
Pargaonmius Westermani/Mexicanus

Question 6

Which parasites cause eosinophilia and skin nodules?

Answer 6

Migratory Nodules:
Gnathostoma Spinigerum
Paragonimus Westermani
Fasciola Hepatica

Fixed Nodules:
Taenia Solium
Oncocerca Volvulus