Neuro - memory Flashcards

1
Q

what is priming

A

the improved ability to detect, produce or classify an item based on a recent encounter with the same or related item

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2
Q

what does an EEG detect when a patient is undergoing word priming and why might that be

A

reduction in cortical activity
could allow for faster perceptual processing

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3
Q

how does the hippocampus integrate information

A

receives highly processed information
compared against sensory cortex - barrel cortex

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4
Q

what does hippocampal plasticity allow for

A

associations to take place

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5
Q

what prevents LTP

A

a selective NMDAR antagonist

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6
Q

what is the main feature of NMDA receptors and why

A

voltage-dependent because of Mg2+ blockade

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7
Q

what can NMDAR act as

A

coincidence detectors

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8
Q

when does NMDAR open

A

only when there is glutamate release
and postsynaptic depolarisation

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9
Q

what is facilitation

A

pronounced short term plasticity

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10
Q

give an example of pre-synaptic short term plasticity

A

unitary EPSP’s are not sufficient to induce a spike in CA3 neurons but cause AP’s if impulses are delivered in bursts
the vesicles are ‘more ready for release’

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11
Q

plasticity-dependent detonation may be critical for what

A

for efficient coding, storage and information recall in the granule cell

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12
Q

what occurs after high frequency stimulation

A

full detonator mode for tens of seconds

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13
Q

what are the advantages of declarative memory

A

flexible
accessible to awareness
guides performance in multiple contexts

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14
Q

what is eyeblink conditioning

A

just before a puff of air is exerted onto eyes - inducing a blink
a beep is produced
leads to beep resulting in a blink

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15
Q

what conditions would impair tests such as eyeblink conditioning

A

cerebellar or brainstem lesions

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16
Q

what is the amygdala activated by

A

fear and strong positive emotions
critical in fear learning

17
Q

how does the amygdala carry out its function

A

enhances memory of strong emotional events
releases stress hormones from adrenal gland
affects forebrain via vagus nerve, nucleus of the solitary tract and the locus coeruleus

18
Q

what is the caudate nucleus

A

component of the basal ganglia
reward system
functions as part of the cortico-basal ganglia-thelamic loop
goal directed behaviour

19
Q

how does disrupted hippocampal function effect the procedural habit memory of rats
and what is the difference with rats with caudal lesions

A

failed when they needed to acquire flexible behaviour
succeeded when they needed to respond repetitively
caudal lesions - opposite outcomes

20
Q

what is the neostriatum

A

important for gradual feedback guided learning
results in ‘gut feeling’

21
Q

what disease effects the neostriatum

A

parkinson’s

22
Q

what happens if you repeatedly stimulate the same synapse

A

it gets bigger
increase in synaptic efficiency

23
Q

what does the hippocampus compare its highly processed information against

A

compared against sensory cortex

24
Q

function of the entorhinal cortex

A

integrates spatial information

25
Q

what is the function of each hippocampal subfield

A

contributing to further processing of high-level information

26
Q

what does hippocampal plasticity allow for

A

allows associations to take place

27
Q

why are NMDA receptors voltage-dependant

A

Mg2+ blockade

28
Q

what are NMDA receptors permeable to

A

Ca2+