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Biochem Drugs > TCA > Flashcards

TCA Flashcards

0
Q

Malonate

A

Analogue (3-C) of succinate; competitive inhibitor of Succinate Dehydrogenase, inhibition causes block of TCA cycle; build up of succinate, citrate, and alpha-ketoglutarate

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1
Q

Fluoroacetate

A

Suicide inhibition of Aconitase; fluorine binds to Fe2+

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2
Q

Trivalent arsenic aka Arsenite

A

inhibits enzymes with lipoic acid enzymes as cofactor, i.e.alpha-KGDH, PDH

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Biochem Drugs (15 decks)

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