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Perio > 13. Modifying factors of periodontitis > Flashcards

13. Modifying factors of periodontitis Flashcards

1
Q

Most important modifying factors in periodontal disease

A
  • Diabetes
  • Hormonal-Puberty, pregnancy, menopause, oral contraceptives
  • Tobacco smoking
    *Osteoporosis
    *HIV
    *Leukemia
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2
Q

Modifying factors have an effect on

A
  • Vascular system
  • Inflammatory response
    *Tissue repair
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3
Q

Modifying factors modify the patients

A
  • Susceptibility to disease
  • Plaque microbiota
  • Clinical presentation of disease
  • Progression
  • Response to treatment
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4
Q

Medications with an effect on periodontal disease

A
  • CCB- Nifidipine
  • Phenytoin-Anticonvulsant
  • Cyclosporin-Immunosuppresant
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5
Q

Pregnancy effect on periodontal disease

A
  • Increaed plasma hormone levels(increased bleeding, gingival overgrowth, exudate and GCF)
  • Estrogen affects salivary peroxidases
  • Inreased growth of seletive pathogens
  • Estrogen increases inflammation
  • Estrogen affects degree of keratinisation of CT ground substance
  • Pregnancy granuloma can develop

salivary perioxidases active against mo

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6
Q

Puberty effect on periodontal disease

A
  • Steroid hormones-increased inflammatory mediators
  • Gingivitis
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7
Q

Menstrual cycle effect on periodontal disease

A

Increased exudate/inflammatory exudate

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8
Q

Menopause effect on periodontal disease

A
  • Decrease in hormonal levels cause tissue changes
  • -> Desquamation of gingival epithelium and osteoporosis

countered by estrogen supplementation

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9
Q

Smoking effect on periodontal disease

A
  • Vasoconstriction->False Bop
  • Deeper pocket depths-AL
  • Decreased salivary flow-xerostomia
  • Fibrotic gingival appearance with little inflammation and edema
  • Poorer oral hygiene
  • Impaired PMN phagocytosis
  • Poorer healing
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10
Q

Diabetes effect on periodontal disease

A
  • Decreased salivary flow
  • Predisposition to candidiasis, burning mouth, abcess formation
  • Impaired healing-poor leukocyte function, reduction in growth and proliferation of CT due to hyperglycemic environment
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11
Q

HIV effect on periodontal disease

A
  • Impaired immune system-infection susceptibility
  • Dry mouth
  • Red band gingivitis
  • PD bone loss
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11
Q

Leukemia effect on periodontal disease

A
  • Increased bleeding
  • Paleness of mucosa
  • Gingival hyperplasia, petechiae and hemorrhages
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12
Q

Osteoporosis effect on periodontal disease

A
  • Increased progession of disease
  • Decreased bone density-mobility
  • Increased inflammatory mediators
  • Bisphosphonate related osteonecrosis of jaws
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13
Q

Oral contraceptive effect on periodontal disease

A

Increase of inflammatory mediators-Prostaglandins, cytokines

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Perio (47 decks)

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