Chorioamnionitis Flashcards

1
Q

Why is choriomanionitis important

A

Main cause of sepsis in pregnancy

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2
Q

Stages of perinneal tears

A

4

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3
Q

What is more common in macrosomic babies

A

Peronneal tears
shoulder dystocia
Post partum haemorrhage- prophylaxis

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4
Q

What is the other main cause in pregnancy of sepsis except chorioamnionitis?

A

UTI

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5
Q

What is choriomanionitis

A

Infection of choriomanitoic membranes and amniotic fluid
Usually occurs in late pregnancy or labour

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6
Q

What is the upper segment of uterus

A

Muscular
Lower segmanet is comparatively thin and less vascular, develops in pregnancy
Heals much better therefore use in C section

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7
Q

What cn choriomnionitis cuased by>

A

Grma +, gram - bacteria
anaerobes

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8
Q

MEOWS

A

Maternal early obstetruc warning system

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9
Q

Non specific signs of sepsis

A
  • Fever
  • Tachycardia
  • Raised respiratory rate (often an early sign)
  • Reduced oxygen saturations
  • Low blood pressure
  • Altered consciousness
  • Reduced urine output
  • Raised white blood cells on a full blood count
  • Evidence of fetal compromise on a CTG
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10
Q

Additional signs and symptoms related to chorioamnionitis causing sepsis

A

Abdominal pain
Uterine tenderness
Vaginal discharge

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11
Q

Additional signs and symptoms related to a urinary tract infection causing sepsis

A
  • Dysuria
  • Urinary frequency
  • Suprapubic pain or discomfort
  • Renal angle pain (with pyelonephritis)
  • Vomiting (with pyelonephritis)
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12
Q

Investigations for choriomanionitis

A
  • Full blood count to assess cell count including white cells and neutrophils
  • U&Es to assess kidney function and for acute kidney injury
  • LFTs to assess liver function and as a possible source of infection (e.g. acute cholecystitis)
  • CRP to assess inflammation
  • Clotting to assess for disseminated intravascular coagulopathy (DIC)
  • Blood cultures to assess for bacteraemia
  • Blood gas to assess lactate, pH and glucose
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13
Q

Additional investigations based on sus source of infection

A
  • Urine dipstick and culture
  • High vaginal swab
  • Throat swab
  • Sputum culture
  • Wound swab after procedures
  • Lumbar puncture for meningitis or encephalitis
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14
Q

Management choruomanipnitis

A

Senior obstetricians and midwives should be involved early in care
Early recongition and management essential
Sepsis six
Continuous maternal and foetal monitoring
May need early delivery
Emergency C section - foetal distress

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15
Q

How anaesthetise women w sus sepsis?

A

General - avoid spinal anaesthetic

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16
Q

Antibiotic regimes for choriomanionitis

A

Piperacillin and tazobactam (tazocin) + gentamycin
Amoxicillin, clindamycin, gentamycin

17
Q

Sepsis 6

A

Three tests:
* Blood lactate level
* Blood cultures
* Urine output

Three treatments:
* Oxygen to maintain oxygen saturations 94-98%
* Empirical broad-spectrum antibiotics
* IV fluids