Blood Flashcards

1
Q

What whole blood consists of

A

Plasma (fluid portion of blood) and formed elements (cellular part of the blood): Erythrocytes (RBC)+leukocytes (WBC)+platelets

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2
Q

Plasma consists of

A

water, proteins, other solutes such as nutrients and ions

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3
Q

% of blood is plasma

A

55%

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4
Q

% of blood is formed elements

A

45%

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5
Q

WBC/leukocytes 2 subclasses are

A

granulocytes and agranulocytes

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6
Q

Granulocytes

A

WBC that have cytoplasmic granules that are visible when stained

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7
Q

Different granulocytes

A

Neutrophils, eosinophils and basophils

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8
Q

different agranulocytes

A

lymphocytes and monocytes

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9
Q

WBC Most->least

A

Neutrophils, lymphocytes, monocytes, eosinophils, basophils

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10
Q

neutrophil recognition

A

multilobed nuclei, most numerous WBC, also called polymorphonucleocytes

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11
Q

Eosinophils recognition

A

tend to have Bilobed nuclei: reacts to eosin(red dye)

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12
Q

Basophils recognition

A

Granules appear dark blue-purple, difficult to find due to being least numerous WBC. interacts strongly with hematoxylin (basic dye dark purple stain)

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13
Q

Lymphocyte recognition

A

Smaller than granulocytes and have a large spherical nuclei. second most common WBC

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14
Q

Monocyte recognition

A

largest WBC have U shaped nuclei. 3rd most numerous

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15
Q

Platelets

A

Small cellular fragments with no nuclei and missing most organelles. used for blood clotting

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16
Q

blood clotting is due to

A

platelets

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17
Q

Blood typing is done by

A

checking the blood for the presence or absence of specific antigens/glycoproteins on the cell surface

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18
Q

Most common blood types

A

O+, A+,B+

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19
Q

What antigens does O blood have

A

None, it has neither A or B

20
Q

How are antigens determined to be on a erythrocyte

A

by combining them with an antiserum solution that will clot/agglutination. Antibodies in the serum cause antigens on erythrocytes to agglutination

21
Q

Blood with RH antigen is considered

A

positive

22
Q

blood without RH antigen is considered

A

negative

23
Q

Hemolysis

A

When recipients antibodies agglutinate foreign erythrocytes and the immune system destroys them. wrong blood given to a recipient causes hemolysis when the recipients immune system recognizes it as foreign.

24
Q

O+ can donate to

A

Any + blood type

25
Q

O+ can receive from

A

O+-

26
Q

O- can donate to

A

Any blood type

27
Q

O- can only receive from

A

O-

28
Q

AB+ can donate to

A

AB+

29
Q

AB+ can receive from

A

Any blood type, universal receiver

30
Q

AB- can donate to

A

AB+-

31
Q

AB- can receive from

A

any negative blood type

32
Q

B+ can receive

A

B+- and O+-

33
Q

B+ can give to

A

AB+, B+

34
Q

B- can receive

A

B-, O-

35
Q

B- can donate to

A

B+-, AB+-

36
Q

A+ can donate to

A

AB+, A+

37
Q

A+ can receive

A

A+-, O+-

38
Q

what antigen cannot be found on the surface of an erythrocyte(RBC)

A

O antigen

39
Q

Which blood type is a universal recipient

A

AB+

40
Q

Which blood type is a universal donor

A

O-

41
Q

Negative blood types can give to the same

A

+ blood types

42
Q

which blood type can take any negative blood types

A

AB-

43
Q

What blood type can give to both A and B

A

AB

44
Q

type O+ can give to

A

any +

45
Q

Why is the O- the universal donor

A

it has no antigens and will not trigger an immune response

46
Q

Why is AB+ the universal recipient

A

has all 3 antigens and no antibodies to the antigens