Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Integrative Nutrition and Pathophysiology > GI 4 > Flashcards

GI 4 Flashcards

1
Q

4 important organs of the GI tract

A
  1. esophagus
  2. stomach
  3. small intestine
  4. colon
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

esophagus function

A

transport food entering mouth to stomach

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

stomach role

A

digestion, some absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

small intestine role

A

absorption and digestion
different micornutrients absorbed in different parts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

colon role

A

fluid/electrolyte absorption
propulsion/holding feces
vitamin produciton (gut microbiome)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

GERD =

A

gastroesophageal reflux disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

GERD is characterized by

A
  1. transient lower esophageal sphincter relaxation
  2. increased intra-abdominal pressure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

dietary triggers of GERD

A

caffeine
alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

lifestyle risk factors for GERD

A

obesity
pregnancy
exercise after eating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

GERD pathophys
increased exposure of esophageal mucosa to __
impacts local microbiome and stimulate __ response
increased intracellular __

A

GERD pathophys
increased exposure of esophageal mucosa to gastric contents
impacts local microbiome and stimulate immune response
increased intracellular permeability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

IBD = __ immune dysregulation due to interaction between __ microbiota and __ immunity

A

IBD = mucosal immune dysregulation due to interaction between intestinal microbiota and host immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

IBD genetics

A

host must be genetically susceptible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

IBD diagnosis

A
  1. symptoms (dermatological, vascular, respiratory, inflammatory)
  2. exams, stool tests, imaging, biopsy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

IBD diagnosis requires high __ (detects inflammation) and low __ (tells us you are in active IBD)

A

IBD diagnosis requires high calprotectin (detects inflammation) and low albumin (tells us you are in active IBD)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

IBD: __ immune defects involving __ receptors

A

IBD: innate immune defects involving pattern recognition receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

IBD also has __ dysfunction that affects __

A

IBD also has epithelial barrier dysfunction that affects mucus secretion, peristalsis, antimicrobial factors

17
Q

IBD also has __ immunity defects

A

IBD also has adaptive immunity defects

18
Q

goal of IBD treatment

A

mucosal healing
absence of ulcerations and erosions

19
Q

pharmacotherapy for IBD

A
  1. steroids (short-term)
  2. aminosalicylates (UC only)
  3. immunosuppressants
  4. biologics
20
Q

what types of remission must we achieve with IBD

A

clinical, serologic, endoscopic remission

21
Q

step-up therapy:
top-down therapy:

A

step-up therapy: nutrition, probiotics, start with antiobiotics, go up to more severe treatments
top-down therapy: start with surgery, supplement with simpler treatment options

22
Q

is current approach to IBD step-up or top-down?

A

top-down!

23
Q

anti-__ meds are effective in treating IBD

A

anti-TNF meds are effective in treating IBD

24
Q

dietary approaches to treat IBD

A
  1. specific carbohydrate diet (SCD)
  2. Crohn’s disease exclusion diet (CDED)
  3. exclusive enteral nutrition (no solid foods)
25
Q

what diet is really bad for IBD?

A

low fiber with food additives increase risk

26
Q

IBS is __, __ abdominal pain with altered __

A

IBS is chronic, recurrent abdominal pain with altered bowel habits

27
Q

prevalence of IBS

A

10-15%

28
Q

IBS makes up __% of referrals to GI

A

IBS makes up 25-50% of referrals to GI

29
Q

__ is the most common funcitonal GI disorder

A

IBS is the most common funcitonal GI disorder

30
Q

8 parts of IBS pathophys

A
  1. dysregulated gut motility
  2. visceral hypersensitivity
  3. inflammation
  4. postinfections
  5. microbiome
  6. food sensitivity
  7. genetics
  8. psychosocial dysfunction
31
Q

IBS inflammation
some patients have increased __ cells/__ and increased __

A

IBS inflammation
some patients have increased inflammatory cells/cytokines and increased permeability

32
Q

IBS and psychosocial dysfunction

A

correlation with traumatic life events
higher rates of mood disorder, suicidal ideation, anxiety

33
Q

IBS food sensitivities

A

fructose
fructans
gliadin
sorbitol
lactose

Integrative Nutrition and Pathophysiology (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions