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PBR FlashCards > Allergy/Immuno > Flashcards

Allergy/Immuno Flashcards

1
Q

triggers for vasomotor rhinitis

A

cold air, tearing, pollution and emotion

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2
Q

gold standard of dx food allergy is

A

oral food test in front of cliniciNS

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3
Q

what kind of allergy testing isnt affected by recent antihistamine use

A

RAST since is a blood test measuring for IgE

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4
Q

C1 esterase deficiency causes whst

A

hereditary angioedema

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5
Q

what medicine blunts the effects of epinephrine and should be reversed if the patient is having anaphyaxis and needs epi

A

beta blocker, give glucagon to reverse

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6
Q

what formula should you use for milk protein allergy

A

hydrolyzed not SOY

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7
Q

is FPIES IgE mediated

A

no

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8
Q

when does FPIES get better

A

as the GI tract matures

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9
Q

Bloody diarrhea or reg diarrhea and emesis in a patient drinking cows formula but not when on clears and eating foods with none whole protein contents , dx?

A

FPIES

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10
Q

what is food protein induced enterocolitis syndrome

A

a severe reaction to an allergen about 1-3 hours after ingestion, severe vomiting and diarrhea (cows milk and soy are culprits)

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11
Q

hydrogen breath test tests for what

A

lactase deficiency

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12
Q

type 3 HS reaction is?

A

immune complex

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13
Q

ype 4 HS reaction is

A

cell mediated ( t cell) “poison ivy”

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14
Q

type 2 HS reaction is

A

antibody mediated “ b cell”

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15
Q

type 1 HS reaxtion is

A

IGE mediated anaphylaxis

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16
Q

what medication blunts the response to epi? what should you give

A

beta blokers, give glucagon to reverse the effects

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17
Q

anaphylactoid reactions happen in reponse to whatr

A

contrast, PCN, vanc, NSAID and opitates

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18
Q

what should be given to prevent an anaphyactoid reaction

A

diphenhydramine and steroids

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19
Q

nephritis, arthralgias, arthritis and or rash after exposure to medication 1-2 weeks prior is known as

A

serum sickness

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20
Q

bee sting reactions are due to what

A

IgE mediated (type 2 HS rxn)

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21
Q

bee sting reactions are due to what

A

IgE mediated (type 2 HS helper t cells rxn)

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22
Q

bee sting reactions are due to what

A

IgE mediated (type 2 HS rxn)

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23
Q

helper t cells

A

CD4

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24
Q

Cytotoxic t cells

A

CD8

25
Q

PJP is found in SCID and HyperIgM but not in

A

Bruton Agammaglobulinemia

26
Q

chronic or recurrent fungal infections is seen in what kind of condition

A

t cell/ combined t cell deficiencies

27
Q

skin testing like ppd check for what kind of HS rexn

A

Type 4

28
Q

SCID is what kind of cell deficiency

A

t AND b cells “ thats why it is called combined”

29
Q

first 3–6 months with otitis media (OM), thrush, diarrhea, and dermatitis.

A

SCID

30
Q

what is the cure for SCID

A

BMT

31
Q

what should SCID patient’s not receive

A

live vaccines

32
Q

what are two common combined t and b cell deficiences

A

wiskott aldrich and SCID

33
Q

lymphopenia is usually in relaiton to what cell line being low

A

t cells

34
Q

what imunoglobulin is increased in WIA

A

IgA, IgM is dereased

35
Q

what test is used to dx digeorge

A

FISH

36
Q

what is an AR condition that involves the ineffective repaire of damaged DNA

A

ataxia telengeictasia

37
Q

1st sig of ataxia telengiectasia

A

cerebellar ataxia around age 1

38
Q

ataxia telengiectasia has an increased risk of malginancy when

A

in the 3rd decade of life

39
Q

ataxia telengiectasia has what kind of recurring illness

A

pneumonia and sinusitis (AFP is high)

40
Q

in what condition do B cells fail to form into plasma cells causing a deficiency of all the Ig subtypes

A

combined variable immunodeficiency

41
Q

a risk of EBV associated lymphoma is seen in

A

CVID

42
Q

recurrent HSV and VZV infections are common in

A

CVID

43
Q

IgM will not class switch to IgG due to a missing signal from t and b cells in what syndrome

A

HyperIgM Syndrome

44
Q

patients with HyperIgM syndrome have wat kind of infections

A

PNA, sinusitis and OM

45
Q

tx for hyperIgM is

A

IVIG

46
Q

how to test for b cell deficiency

A

obtain titers

47
Q

condition where there are no b cells so no immunoglobulins

A

x linked agammaglobulinemia

48
Q

when you see b cell, think of what kind of infection

A

bacterial

49
Q

ch50 is a great test to tell between XLA agammaglbulinemia and C1-C4 esterase deficiency how?

A

CH50 is nl in XLA and low in C1-C4 complement deficiency

50
Q

this condition:
- presents at 6 month
- only in boys
- recurrent bacterial infections (encapsulated)
- lack of B cells ( aka no Ig’s )
- High T cells

A

X linked agammaglobulinemia

51
Q

tx for XLA

A

IVIG, abx ppx or BMT is curative

52
Q

transient hypogammaglobulinemia of infance has low what

A

IgG and IgA, gets better by age 3-6

53
Q

eosinophils high, eczema and high IgEis

A

Hyper IgE syndrome

54
Q

delayed shedding of primary dentition is seen in

A

Hyper IgE

55
Q

impaired neutrophil chemotaxisi ( aka no erythema at infection sites) is seen in what condition

A

Hyper IgE

56
Q

which complement deficiency is related to herditary angioededma

A

C1 esterase deficiency

57
Q

neutropenia, oculocutaneous albinism, low platelets and recurrent indection with staff, what is the confition

A

chedik higashi syndrome

58
Q

pancreatic insufficiecny + pancytopneia

A

schwachman diamond syndrome

59
Q

pure red cell aplpasia (only red cell line affected) + triphalngeal thumb+macrocytosis

A

diamond blacfan anemia

PBR FlashCards (13 decks)

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