acute tubular necrosis

Question 1

definition of acute tubular necrosis

Answer 1

cell death of tubular epithelial cells in renal tubules

Question 2

causes of acute tubular epithelial cells

Answer 2

hypotension, nephrotoxins (hemoglobin/myoglobin, aminoglycosides, statins, bisphosphonates

Question 3

investigations for acute tubular necrosis

Answer 3

urine microscopy (muddy brown casts), renal tubular epithelial cells)

AKI (fe na 2+), increased serum ck, decreased urine output

Question 4

treatment for acute tubular necrosis

Answer 4

stop nephrotoxic agents, IV fluids, takes 21 days to recover