Cilia and Ciliopathies Flashcards

1
Q

what is an axoneme

A

central structure of cilium consisting of 9 pairs of microtubules surrounding a central pair
(9+2)

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2
Q

what is the basal body

A

this is the structure at the base of cilium that anchors it to the cell and provides site for assembly of axoneme

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3
Q

what is Dynein
driving causes dying

A

motor protein that drives the movement of cilia by hydrolysing ATP to slide the microtubules against eachother

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4
Q

what is Nexin

A

links adjacent microtubules in the axoneme to maintain structure of cilia

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