Ciliary growth and its relationship to the stages of cell cycle

Question 1

how many stages are there in the cell cycle

Answer 1

5

Question 2

what occurs in G1

Answer 2

formation and assembly of basal body
centrioles replicate and migrate to the cell surface
basal body anchors cilium to cell membrane

Question 3

what occurs in the S stage

Answer 3

axoneme is formed
microtubules are assembled to form tubulin subunits and form 9+2 pattern

Question 4

what occurs in G2

Answer 4

axoneme elongates and becomes fully functional: allowing cilium and begin specific functions
length of shape of cilium tightly regulated by several signalling pathways

Question 5

what occurs in the M phase

Answer 5

cilium is disassembled as cell prepares to divide
basal body and associated proteins are segregated to daughter cells

Question 6

give a short summary of cell cycle

Answer 6

G2 and S: assembly and elongation of cilium
M: Disassembly of cilium