Neuropathology Flashcards
1
Q
What does this show
A
Cytoplasmic neuronal vacuolation in spongiform encephalopathies
Round clear space within cytoplasm of neurons
e.g. scrapie
2
Q
What are routes of entry into the brain
A
Haemotogenous (streptococci)
Intraaxonal (rabies)
Direct extension (from sinusitis, otitis, abcesses etc.)
Within leucocytes (canine distemper virus)
3
Q
Types of degenerative diseases
A
Metabolic-toxic diseases (e.g. grass sickness in horses)
Nutritional diseases (selenium poisoning in pigs)
Hereditary diseases (storage diseases)
4
Q
What is cerebral cortical necrosis
A
Necrosis of grey matter
Clear spaces start to appear in deep cortex
Caused by thyamine deficiency
5
Q
What does this show
A
Swollen neurons due to (lysosomal) storage disease
