Neoplasia nonsense

Question 1

primary neoplasms of kidney

Answer 1

• relatively uncommon in dogs

- rare in all other species

Question 2

benign primary renal neoplasms (4)

Answer 2

• renal cell adenoma
• ondocytoma
• fibroma
• hemangioma

Question 3

malignant primary renal neoplasms (4)

Answer 3

• renal carcinoma
• nephroblastoma
• transitional cell carcinoma
• hemangiosarcoma

Question 4

renal carcinoma

Answer 4

• most common primary renal tumor
• dogs, cats, horses
• often metastatic when clinical signs evident
• usually unilateral, may be bilateral or multiple masses within one kidney

Question 5

nephroblastoma

Answer 5

• primary renal tumor
• pigs, chickens, dogs, cats
• unilateral at one pole and within cortex –> lobulated appearance

Question 6

transitional cell carcinoma (renal)

Answer 6

• uncommon primary renal tumor

- arise in renal pelvis from transitional epithelium

Question 7

hemangiosarcoma

Answer 7

• rare primary renal tumor

- much more common as metastatic renal tumor (secondary)

Question 8

secondary renal neoplasms (4)

Answer 8

• lymphoma (lymphosarcoma)
• hemangiosarcoma
• malignant melanoma
• carcinomas

Question 9

lymphoma (lymphosarcoma)

Answer 9

• secondary renal neoplasm
• most common neoplasm in cat kidneys
• neoplastic lymphocytes
• can lead to chronic renal failure

Question 10

hemangiosarcoma

Answer 10

• secondary renal neoplasm

- neoplastic endothelial cells forming irregular blood-filled vascular channels

Question 11

malignant melanoma

Answer 11

• secondary renal neoplasm
• neoplastic melanocytes
• cortex and medulla affected

Question 12

renal carcinomas

Answer 12

• secondary renal neoplasm

- renal metastases from mammary, thyroid, etc carcinomas

Question 13

renal pseudotumors (3)

Answer 13

• granulomas (systemic fungal infections, FIP)
• simple (developmental) cysts
• polycystic kidney disease

Question 14

polycystic kidney disease

Answer 14

• young cats: autosomal recessive trait
• adults: autosomal dominant trait (persian cats)
• leads to renal failure

Question 15

benign lower urinary tract neoplasms (2)

Answer 15

• papilloma (polypoid masses in mucosa to bladder)

- leiomyoma (muscular wall of bladder)

Question 16

malignant urinary tract neoplasms (3)

Answer 16

• transitional cell carcinoma
• squamous cell carcinoma
• leiomyosarcoma
• rhabdomyosarcoma

Question 17

transitional cell carcinoma (urinary)

Answer 17

• most common primary renal tumor in urinary bladder (very metastatic)
• seen in areas with enzootic hematuria due to bracken fern consumption
• trigone region of bladder, urethra
• may block urine outflow
• neoplastic urothelial cells

Question 18

bovine enzootic hematuria

Answer 18

• chronic ingestion of bracken fern produces neoplastic syndrome
• hematuria and urinary bladder tumors (TCC)
• thiaminase, bleeding factor
• ptaquiloside

Question 19

squamous cell carcinoma

Answer 19

• most common primary urinary bladder tumor in horses (uncommon in other species)
• thickened plaque-like areas in bladder mucosa
• invade bladder wall but don’t metastasize (usually)

Question 20

leiomyosarcoma

Answer 20

• primary urinary neoplasm (metastases uncommon)
• uncommon in all species
• neoplastic smooth muscle cells

Question 21

rhabdomyosarcoma

Answer 21

• rare primary tumor of urinary bladder and urethra in young, large breed dogs
• botryoid (grape-like) masses
• local invasion, metastatis to lymph nodes

Question 22

secondary neoplasms of urinary tract

Answer 22

• lymphoma

- others are rare

Question 23

urinary tract pseudotumors

Answer 23

polypod cystitis (associated with chronic urocystitis, urolithiasis)