SUD vs. GD

Question 1

Difference SUD GD

Answer 1

• Biological component of substance
• Predictability: Known reward in SU
• Effect on the brain (neurotoxic)
• Dopamine release always happens and is quick and strong in NAcc (direct vs indirect reinforcement in GD, incentive sensitisation)

Question 2

Reward uncertainty

Answer 2

A factor that makes gambling addictive. The varied ratio and different probability.

In monkey study:
- Cues that always predict or never predict
- Cue with 50% chance. Dopamine fires at cue onset, but also slowly rises in anticipation of the possible reward.

Caused the highest dopamine activity