microcytic anaemia

Question 1

icrocytic anaemia, the causes of which can be broadly categorised into

Answer 1

1, iron deficiency,
2, thalassaemia trait
3, sideroblastic anaemia.

Question 2

iron deficiency anaemia blood results ?

Answer 2

normal transferrin saturation and normal ferritin

Question 3

thalessemia diagnosis ?

Answer 3

Hb electrophoresis

Question 4

sideroblastic anemia diagnosis ?

Answer 4

high ferritin
high iron
high transferrin saturation

blood film
basophilic stippling of red blood cells

bone marrow
Prussian blue staining will show ringed sideroblasts

Question 5

what is sideroblastic anemia ?

Answer 5

red cells fail to completely form haem, whose biosynthesis takes place partly in mitochondrion.

leads to deposits of iron in mitochondria that form a ring around the nucleus called a ring sideroblast.

Question 6

congenital cause o sderoblastic anemia ?

Answer 6

delta-aminolevulinate synthase-2 deficiency

Question 7

acquired cause of sideroblastic anemia ?

Answer 7

myelodysplasia
alcohol
lead
anti-TB medications