Exam #4

Question 1

What is absorption?

Answer 1

from site of entry to blood stream

Question 2

what is distribution?

Answer 2

drug molecules move from blood throughout the body

Question 3

what is metabolism?

Answer 3

breakind down the drug into metabolites

Question 4

what is excretion?

Answer 4

removal of the drug and or metabolites from the body

Question 5

what organ handles excretion?

Answer 5

kidney

Question 6

what is the order from slowest to quicker absorption?

Answer 6

oral, rectal, sub cutaneous, intramuscular, buccal/sublingual, endotracheal/inhaled, intravenous

Question 7

what are iatrogenic effects?

Answer 7

development of disorder through drug therapy

Question 8

what is an example of iatrogenic effects?

Answer 8

cancer patient receiving chemo gets neutropenia

Question 9

what is the treatment for mild to moderate allergic reaction?

Answer 9

antihistamine and corticosteroids

Question 10

what are the treatments for anaphylactic?

Answer 10

epi, antihistamine, corctico, iv, bronchodialtors, O2

Question 11

what is the idiosyncratic effect?

Answer 11

unusual or peculiar respsone to a drug

Question 12

what is an additive effect?

Answer 12

drugs with similar MOA produce a greater effect

Question 13

what is synergistic displacement?

Answer 13

drugs with different MOA potentiate each other

Question 14

what is the antagonistic effect?

Answer 14

combined drugs negate each other

Question 15

what is interference?

Answer 15

one drug interferes with metabolism of other drug and builds up in the system leading to toxicity

Question 16

what is displacement?

Answer 16

one drug bind to the site of the other building up and leading to toxicity

Question 17

what is the expected healthy weight and age ?

Answer 17

150lbs and 18 to 65