Exam #4 Anticoagulants Flashcards

1
Q

what is the ending for anticoagulants?

A

in

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2
Q

what are the two anticoagulants?

A

warfarin and herparin

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3
Q

what is the therapeutic class for warfarin?

A

anticoagulatns

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4
Q

what is the pharma class for warfarin?

A

coumarin derivatives

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5
Q

what is the pharma action/how does warfarin work?

A

antagonizes Vitamin K

prevent coagulation of factor VII and Factor IX

prothrombin

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6
Q

what is the therapeutic use/ what does warfarin treat?

A

PE

DVT

MI

Prosthetic HV

Chronic afib

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7
Q

what is the adverse effects of warfarin?

A

hemorrhage….blood in stool or urine…bruising

Hepatitis

Toxicicty

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8
Q

what are the contraindications for warfarin?

A

pregnancy…breast feeding

low platelet

vitamin K dif

Recent surgery

Liver disorder

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9
Q

what should you monitor when giving warfarin?

A

INR

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10
Q

what does INR measure?

A

the level of blood clotting

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11
Q

what is the range for INR?

A

1 in healthy people…2-3 on anti coag

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12
Q

what should you avoid on warfarin?

A

eating Vitamin K….leafy greens

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13
Q

what is the therapeutic class for heparin?

A

anticoagulants

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14
Q

what is the pharmacological class for heparin?

A

anticoagulatns

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15
Q

what is the pharmacological action/ how does heparin work?

A

prevents clotting

inactivates thrombin and factor Xa

inhibits fibrin formation

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16
Q

what are the therapeutic uses for heparin?

A

PE

CVA

DVT

MI

Prosthetic heart valves

17
Q

what are the adverse side effects for heparin?

A

hemorrhage

heparin induced thromcytopenia

hyerkalemia

18
Q

what are the contraindication for heparin?

A

low platelet

vitamin K dif

Recent surgery

Liver disorder

19
Q

Antidote for warfarin?

A

Vitamin k … leafy greens

20
Q

Antidote for heparin?

A

Protamine sulftate