Body fluids

Question 1

TBW is how much of body weight

Answer 1

0.6

Question 2

is ECF left or right in diagram

Answer 2

left

Question 3

is ICF left or right in diagram

Answer 3

right

Question 4

how much of ECF is the interstitial fluid

Answer 4

3/4

Question 5

how many liters in interstitial fluid

Answer 5

10.5

Question 6

where is plasma how much is there

Answer 6

in ECF side
1/4

Question 7

how many liters ICF side

Answer 7

28 liters

Question 8

ICF is how much of TBW

Answer 8

2/3

Question 9

TBW in volume

Answer 9

42 L

Question 10

ICF volume

Answer 10

28 L

Question 11

ECF volume

Answer 11

14 L

Question 12

Average osmolarity of TBW ICF and ECF

Answer 12

300

Question 13

average TBW osmoles

Answer 13

12600 mOsm

Question 14

average ICF osmoles

Answer 14

8400

Question 15

average ECF osmoles

Answer 15

4200

Question 16

First thing to do when answering questions

Answer 16

identify which compartment is being measured . look at TRACERS

Question 17

tracer- 3H20 (tritium labeled water)

Answer 17

TBW

Question 18

tracer inulin

Answer 18

EXTRACEULLUAR FLUID ECF

Question 19

always start with TBW for every calculation. WHATS THE EQUATION

Answer 19

Vol = quantity (mass) / Concentration

Question 20

Evans blue dye measures which compartments

Answer 20

Plasma (the dye binds to plasma proteins

Question 21

what are the two ways to calculate blood volume

Answer 21

hematocrit or via the tagging of pt RBCs with radio chromium

Question 22

if plasma volume is not found we have to calculate it using what equation

Answer 22

V= Q/C

Question 23

True or False

Hematocrit will always be given as a percent but we need to express it as a fraction so we can substract it from 1

Answer 23

TRUE

Question 24

practice drawing boxes

Question 25

read haramatis handouts

Question 26

osmolarity = ?

Answer 26

mass/volume

Question 27

major components of plasma

Answer 27

Na+, Cl-

Question 28

major components of interstitial fluid

Answer 28

Na+, Cl-

Question 29

major components of Intracellular Fluid

Answer 29

K+

Question 30

Indicator dilution technique: The plasma compartment has protein, while the IF doesn’t, therefore to measure plasma compartment you inject radiolabeled protein. In the ECF you inject a Na+ isotope or a small sugar that doesn’t cross cell membranes (insulin). In the IF you use plasma tracer and an ECF tracer and subtract to get IF.

Question 31

Indicator dilution technique - what solutes would you choose to measure each compartment of the body fluids?

radiolabeled proteins = plasma
Na+ or small sugar that can’t cross cell membraine (inulin) = ECF
plasma tracer and ECF tracer = IF (ECF-plasma =IF)

Question 32

Volume of any compartment in the body can be determined by the following equation: Volume (V2) = (C1 x V1)] /C2 where C is concentration.
Example: If 10 mg of a dye was placed in a compartment and after complete dilution of the dye its concentration was 0.01 mg/ml, the volume of the compartment calculates to 1000 ml (or 10 mg/0.01 mg/ml).

Comes from C1V1 = C2V2

Question 33

Calculation of Blood Volume:
1. Hematocrit = Fraction of RBC/BV (usually expressed as percent)
2. Blood volume (BV) = plasma volume/1-Hematocrit (expressed here as a fraction)