1.4 Morphological and functional development of the fetus Flashcards

1
Q

is the time elapsed since last menstrual period

A

Menstrual Age/ Gestational Age

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2
Q

time for ovulation used by embryologists

A

Ovulation/Post concepetion/Fertilization Age

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3
Q

divides the period of gestation into 3 units of calendar months

A

Trimesters

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4
Q

4 important events at the 1st 2 weeks of life

A

Ovulation
Fertilization
Blastocyst formation
Implantation

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5
Q

Where does fertilization occur?

A

Ampulla of Fallopian tube

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6
Q

4 possible results of (+) PT

A
  1. Unembryonic
  2. Blighted
  3. Ectopic
  4. Normal pregnancy
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7
Q

the term used for a conception between 3rd week to before 8th week

A

Embryo

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8
Q

lenth of chorionic sac at 3rd week after ovulation (5th gestational age)

A

1 cm

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9
Q

features at 5th week of gestation

A

formed embryonic disc
(+) PT
body stalk differentiated

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10
Q

4th week after ovulation, what are the developments?

A
Heart and pericardium prominent
detectable pulsation
arm/leg buds present
body stalk is now an umbilical cord
Embryo: 4-5mm in length
Chorionic sac: 2-3 cm in daimeter
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11
Q

when are the following observable:
Head bigger than the trunk
Fingers/toes present

A

6th week after ovulation/8th Gestational Age

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12
Q

what is the length of the embryo by 6th week after ovulation/8th Gestational Age?

A

22-24mm

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13
Q

the term used for a product of conception from 8 weeks until birth

A

Fetus

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14
Q

the length of fetus at 8 weeks

A

4cm

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15
Q

uterus palpable at the level of the symphysis pubis @ what age?

A

12th gestational week

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16
Q

earliest time possible for the OB-GYN to detect the sex of the fetus

A

12th gestational week

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17
Q

the age of gestation when by Ultrasound, the fetus is echogenic and appear white

A

12 weeks

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18
Q

CRL (crown-rump Length) @ 12 weeks?

A

6-7 cm

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19
Q

describe the fetus @ 16 weeks as to:
CRL
Weight
Fundus palpable region

A

CRL: 12 cm
Weight: 110g
Fundus palpable region: between symphysis pubis and umbilicus

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20
Q

when is the midpoint of pregnancy?

A

20 weeks (no longer an abortus)

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21
Q

fundus is palpable where @ 20 weeks

A

level of umbilicus

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22
Q

what is the weight of the fetus @ 20 wks?

A

300g

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23
Q

weight of the fetus by 24 weeks

A

630g

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24
Q

when do eyebrows and eyelashes start to appear in a fetus?

A

24th week (gestational)

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25
describe the fetus at 28th week as to: CRL Weight
CRL: 25cm Weight: 1100g
26
what is covering the skin of the fetus at 28th week of gestation?
Vernix caseosa
27
T/F. as long as the skin of the fetus is no longer transparent, the infant can survive if born.
True. but with expert care
28
What is the CRL of a fetus @: 32 weeks 36 weeks 40 weeks
32 weeks: 28 cm 36 weeks: 32 cm 40 weeks: 36 cm
29
what is the fetal weight at the following weeks: 32 weeks 36 weeks 40 weeks
32 weeks: 1800 g 36 weeks: 2500 g 40 weeks: 3400 g
30
average diameter of the pelvis
10 cm
31
what is a contracted pelvic?
pelvis with a diameter of <8cm
32
what are the 5 skull bones? (identify paired/unpaired)
``` 2 Parietal 2 Frontal 2 Temporal 1 Occipital 2 Wings of sphenoid ```
33
membranous spaces separating skull bones
Sutures
34
define the suture: | between 2 frontals
Frontal suture
35
define the suture: | either side between the inferior margin of the parietal bone and upper margin of the temporal bone
Temporal Suture
36
define the suture: | between frontal and parietal bones
coronal suture
37
define the suture: | between the post.margin of parietal bone and upper margin of occipital bone
Lambdoid suture
38
an irregular space where several sutures meet and is enclosed by a membrane
Fontanel
39
What are the 3 fontanels?
Greater/anterior Lesser/posterior Temporal/Casserian
40
the head circumference with greatest length
Occipitofrontal (11.5 cm)
41
ideal diameter for vaginal delivery is 9.5cm which is the measurement of what head circumference?
Biparietal (9.5 cm)
42
the head circumference that is flexed at birth for delivery
Suboccipetobregmatic (9.5 cm)
43
adaptation of the fetal skull to the maternal pelvis
Molding
44
it functions as the lungs, GIT, kidneys for the fetus. what is the normal volume?
Chorionic villi + Intervillous space (140ml at term)
45
Primary biological compartment of the maternal transfer
Intervillous space
46
volume of Uteroplacental blood flow
700ml-900ml
47
histologic barriers of the placental transfer (3)
Syncytiotrophoblast Stroma of intervillous space Fetal capillary wall
48
Type/modes of placental transfer
Diffusion Selective transfer & Facilitated diffusion Specific receptor mediated mechanisms
49
What type of placental transfer> a) Anesthetic gases b) Iron c) Vitamin C d) IgG
a) Diffusion b) Selective transfer & Facilitated diffusion c) Selective transfer & Facilitated diffusion d) Specific receptor mediated mechanisms
50
the major nutrient of fetal growth
Glucose
51
anultrafiltrate of plasma in early pregnancy
Amniotic fluid
52
``` describe amniotic fluid @: Early pregnancy 4 months 2nd trimester 20 weeks ```
Early pregnancy: amniotic fluid from amniotic membrane 4 months: fetus facilitates in amniotic fluid (swallowing, respiring) 2nd trimester: reflects composition of fetal plasma 20 weeks: amniotic fluid composed of fetal urine
53
when do fetal kidneys start producing urine?
12 weeks
54
describe the volume changes in amniotic fluid
@ 8 weeks: volume increase by 10mL/ week @ 21 weeks: increase by 60mL/week @ 33 weeks: decrease back to a steady state
55
Define the terms: oligihydramnios polyhydramnios
oligihydramnios: <500mL of amniotic fluid @ term polyhydramnios: 2000mL of amniotic fluid @ term
56
7 functions of the Amniotic fluid
1. Physical protection 2. Lung expansion 3. EGF 4. PTH-rP 5. Musculoskeletal development 6. Maintain even temperature 7. Cervical dilator @ labor
57
3 shunts present at the fetal circulation
Ductus venosus Foramen ovale Ductud Arteriosus
58
Umbilical Vein functionally close at: Physically close at:
functionally close at: 0-96 hrs | Physically close at: 2-3 weeks
59
atrophied and obliterated umbilical artery forms the
Umbilical ligament
60
Intra-abdominal remnant of the umbilical vein
Ligamentum Teres
61
constricted ductus venosus
Ligamentum venosum
62
Site of hemopoiesis @ 0-12 weeks
Yolk sac (mesoblastic)
63
Site of hemopoiesis @ 16 weeks
Liver, Spleen (hepatic)
64
the volume of the fetoplacental volume at term
125ml/Kg
65
Hemoglobin-globin differences from the adult (3)
Primitive forms HgF HgA
66
when does a fetus start to produce procoagulants, fibrinolytic and anticoagulant proteins
12 weeks
67
fetal fibrinogen appears at
5 weeks
68
IgG is transported to the placenta ___. the bulk is acquired at _______. adult values are obtained at _____.
16 weeks last 4 weeks of pregnancy 3 years of age
69
spinal cord extends at these during? S1 L3 L1
S1: 24 weeks L3: Birth L1: adult
70
persitalsis appears @
11 week
71
fetus absorbs water from swallowed amnion @
16th week
72
how is meconium formed?
hypoxia --> (+)AVP --> (+) colon smooth muscle to contact --> defecation
73
functional immature kidneys
Metanephros
74
anuria of fetus causes
oligohydramnios
75
respiration detected @
11 WEEKS
76
stages of lung development
1. pesudoglandular (5-17 week) 2. Cannalicular (16-25 weeks) 3. Terminal sac (34th week)