Chapter 1 Flashcards

1
Q

What is genetics?

A

The study of biological information passed on from one generation to the next (heredity).

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2
Q

What are the ten reasons genetics is important?

A

– Lives
– Diseases and Disorders
– Agriculture
– Biotechnology and Medicine
– Economic impact
– Legal impact
– Philosophical impact
– Study of Biology

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3
Q

What is a gene?

A

A unit of hereditary information, a sequence in the DNA that codes for something.

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4
Q

What is a genome?

A

A complete set of genetic instructions for any organism

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5
Q

What is the difference between a gene and a genome?

A

A gene is a specific segment of DNA that tells cells how to function. A genome is the entirety of the genetic material inside an organism

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6
Q

What is the Central Dogma of Molecular Biology?

A

A theory stating that genetic information flows only in one direction, from DNA, to RNA, to protein, or RNA directly to protein

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7
Q

What is a Model genetic organism?

A

organisms with characteristics that make them useful for genetic analysis

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8
Q

What are six types of model genetic organisms?

A

Fruit fly, bacterium, nematode, thale-cross plant, house mouse, baker’s yeast.

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9
Q

What are some characteristics of model genetic organisms?

A

-Short generation time
-Production of numerous progeny
-The ability to be reared inexpensively in a lab environment

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10
Q

What are the three divisions of genetics?

A
  1. Transmission genetics (punnett squares, inheritance, gene mapping).
  2. Molecular genetics (Central Dogma).
  3. Population genetics (Entire populations genetics).
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11
Q

What is the difference between Eukaryotic and Prokaryotic?

A

Eukaryotic cells are cells containing membrane-bound organelles and are the basis for both unicellular and multicellular organisms. In contrast, prokaryotic cells do not have any membrane-bound organelles and are always part of unicellular organisms

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12
Q

Eukaryotic Cell

A

Any of the single-celled or multicellular organisms whose cell contains a distinct, membrane-bound nucleus (Animal and Plant cells).

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13
Q

Prokaryotic cells

A

Cells that do not have a true nucleus and membrane-bound organelles (Bacterium and Archea).

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14
Q

What is the long informal history of genetics?

A
  1. Domestication of plants and animals
  2. Selective Breeding
  3. Ancient Greeks- theories of inheritance
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15
Q

What was Pangenisis and the Inheritance of Acquired Characteristics? (Ancient Greeks)

A

Pangenesis- Genetic information travels from different parts of the body to reproductive organs.
Inheritance of Acquired Characteristics -Acquired traits become incorporated into hereditary information.

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16
Q

What early concepts of heredity were correct?

A
  1. Germ-Plasm Theory- All cells contain a complete set of genetic information.
  2. Cell Theory- All life is composed of and cells arise only from cells.
  3. Mendelian Inheritance- Traits are inherited according to specific principles proposed by Mendel.
17
Q

What early concepts of heredity were incorrect?

A
  1. Pangenesis
  2. Inheritance of Acquired Characteristics
  3. Preformationism- Miniature organism resides in sex cell; thus all traits are inherited from one parent
  4. Blending Inheritance- Genes blend and mix
18
Q

What are 11 important Genetics Theories discussed in class?

A
  1. Schleiden and Schwann: Cell theory
  2. Darwin: Evolution through Natural Selection
  3. Mendel: Principles of heredity
  4. Flemming: Chromosomes
  5. Weismann: Germ-plasm theory
  6. Sutton: Genes are located on chromosomes
  7. Watson, Crick, Franklin, and Wilkins: DNA structure
  8. Gilbert and Sanger: DNA sequencing
  9. Mullis: PCR
  10. Human Genome Project
  11. Doudna and Charpentier: CRISPR/CAS9
19
Q

What was Gregor Mendel’s Three Principles of Heredity?

A

Dominance, segregation, and independent assortment.

20
Q

Schleiden and Schwann

A

Cell theory

21
Q

Darwin

A

Evolution through natural selection

22
Q

Mendel

A

Principles of heredity

23
Q

Flemming

A

Chromosomes

24
Q

Weismann

A

Germ-plasm Theory

25
Q

Sutton

A

Genes are located on the chromosome

26
Q

Watson, Crick, Franklin, and Wilkins

A

DNA structure

27
Q

Mullis

A

PCR

28
Q

Tenth genetic theory we covered

A

Human Genome Project

29
Q

Doudna and Charpentier

A

CRISPR/CAS9

30
Q

Gilbert and Sanger

A

DNA sequencing