Stabilité génétique Flashcards

1
Q

Quels sont les 2 Processus qui assure la stabilité génétique

A

replication + reparation erreurs et mitose + points de controles

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2
Q

dessiner meselson et stahl

A

.

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3
Q

3 caractéristique de la réplication

A

semi-conservative, bidirectionnelle et asymétrique

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4
Q

Initiation replication

A

topoisomérase
Helicase + SSB protein + Primase avec amorce ARN

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5
Q

Elongation replication

A

DNA pol III + frgmt Okasaki
ADN pol I qui remplace ARN par ADN
Ligase entre okasaki

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6
Q

Terminaison replication

A

Raccourssissement Telomere sauf cell germinales et cancereuses (telomérases)

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7
Q

Réparation erreur

A

NER BER Mésappariement base

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8
Q

BER

A

Desamination, depurination, me ADN

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9
Q

dessiner NER

A
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10
Q

dessiner BER

A
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11
Q

dessiner initiation et elongation replication

A
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12
Q

dessiner mitose

A
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13
Q

prophase

A

Compaction ADN en chr double
Disparaition nucleole et frgmtation enveloppe nucleaire
Formation µt et fuseaux itotiques

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14
Q

Métaphase

A

Kinétochore plan equatorial
µt associés aux kinétochore
Chr alignés sur la plaque

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15
Q

Anaphase

A

Spération chrtines soeurs
Rupture centromere
migration poles opposés par raccourcissement µt

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16
Q

Télophase

A

Formation anneau contractile
Chr simples
Decompaction et reformation noyau

17
Q

Cytodierese

A

Separation cellules filles + env nucleaire + nucléole

18
Q

Quels points de controle

A

G1/S G2/M et Metaphase/anaphase (controle kinetochore)

detection et reparation anomalie de replication et des lésion de l’ADN