Penicillins Flashcards
Penicillin G (benzylpenicillin)
IV
Pfizerpen
IV
Penicilin G procaine
IM
Wycillin
IM
Penicillin G benzathine
IM
Bicillin L-A
IM
Penicillin G procaine and benzathine
Bicillin C-R
Penicillin VK ( phenoxymethyl penicillin)
PO
Pen-vee K, Veetids
PO
MOA of Penicillin
inhibit cell wall synthesis by binging to penicillin binding protein
Elimination of penicillin
renal
Side effects of penicillin
PCN allergy
seizures
GI
procaine formula:
dizziness, palpitations,
auditory or visual disturbances,
fear of impending death resolves within 15-30 mins
Pregnancy category of Penicillin
B
PCN G (IV, IM, SC)
susceptible to break down in gastric acid
IV= severe or complicated infections
IM= cleared rapidly from the body
Spectrum activity of Penicillin
good activity against no b-lactamase producing gram positive and gram negative, limited gram negative activity
Gram Positive of Penicillins
Streptococcus A (S. pyogenes)
Streptococcus B (s. agalactiae)
Streptococcus C,F, and G
Streptococcus pneumoniae
Streptococcus virdans group
Entercoccus app
Bacillius spp.
Corynebacterium spp
gram neg of Penicillins
Neisseria meningitidis
pasturella multacida
anaerobes for penicillin
Closteridium spp. (exclude c. difficile)
peptostreptoccus spp.
cutibacterium spp.
spirochetes of penicillin
treponema palladium
Leptospira interrogans
penicillins have no staph (T/F)
True
Penicillin is mostly (GN/GP)
GP
Penicillin is bactericidal or bacteriostatic
bactericidal
Penillicinase-resistant (aka antistaptylcoccal) penicillins purpose
the emergence of penicillinase producing stapylococci spp.
examples of Penillicinase-resistant (aka antistaptylcoccal) penicillins
oxacillin, nafcillin, dicloxacillin