lecture 11 - allergy & hypersensitivity

Question 1

What is main type of hypersensitivity involved in allergic reactions?

Answer 1

Type I

Question 2

What is the type of hypersensitivity often associated with the later stages of an allergic response?

Answer 2

Type IV

Question 3

What are the 3 components required for an allergic response?

Answer 3

1. Allergen/antigen
2. Serum factor (IgE)
3. Tissue factor (mast cells)

Question 4

What mediates Type I hypersensitivity allergic reactions?

Answer 4

IgE

Question 5

What type of cell is initially activated in an allergic reaction?

Answer 5

Mast cells

Question 6

What is atopy?

Answer 6

The tendency to allergic reactions/hypersensitivity

Question 7

What is released from mast cells to create allergy symptoms?

Answer 7

Histamine, other chemical mediators

Question 8

What antibodies are involved in Type II hypersensitivity?

Answer 8

IgM/IgG

Question 9

What antibodies are involved in Type III hypersensitivity?

Answer 9

IgG

Question 10

What type of immune cell is involved in type IV hypersensitivity?

Answer 10

T cells

Question 11

What type of hypersensitivity is involved with contact dermatitis?

Answer 11

Type IV - takes a while for symptoms to develop