Oral Mucosal Disease Flashcards

1
Q

When and where is referral needed for oral medicine?

A

Anything dentist believes may be cancer or dysplasia

  • must be put through 2 week cancer referral pathway

Any symptomatic lesion that has not responded to treatment

  • hospital referral criteria

Any benign lesions the patient cannot be persuaded is not cancer

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2
Q

Describe the structure of the oral mucosa

A

Stratified squamous epithelium

Stratum corneum - cornified cells
Stratum granulosum - maturation cells
Stratum spinosum - progenitor cells
Basal layer
Lamina propria
Submucosa

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3
Q

What is acanthosis?

A

Hyperplasia of stratum spinosum

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4
Q

Give some mucosal reactions to pathology / trauma / disease etc

A

Keratosis

Acanthosis

Ulceration

Erosion

Oedema - intra or intercellular

Blister

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5
Q

What may cause a loss of papillae on tongue - smooth surface

Any issues?

A

Iron or b group vitamin deficiency

Atrophy

Predisposition to infection ?

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6
Q

Give some benign mucosal changes

A

Geographic tongue
1-2 % pop

Black hairy tongue
- papillae hyperplasia and bacterial pigment

Fissured tongue

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7
Q

Diagnose and what is aetiology and symptoms

A

Geographic tongue

Alteration in maturation and replacement of normal epithelial surface - in random areas

Works in young children, intermittent symptoms that can be sensitive with acidic or spicy foods

Symptoms only when geographic tongue? Take photo of tongue when symptoms arise

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8
Q

Diagnosis, aetiology, tx?

A

Black / brown hairy tongue

Often soft, or liquid diet can cause thickening and then staining from chlorhexadine, tea, coffee etc

Improved by removing elongated surface with tongue scraper, or harder natural item such as a peach stone sucked round mouth for her a day etc.

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9
Q

Diagnosis, aetiology, tx?

A

Fissured tongue

Tongue just can naturally be fissured

Deep fissures can cause bacterial build up/ candida or lichen planus in fissures so soft brush needed to clean them

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10
Q

Diagnosis? Aetiology and tx? Any symptoms?

A

Glossitis - inflammation of the tongue
- Smooth and red atrophy tongue
- Haemotinics taken as often caused by vitamin deficiencies
- Also biopsy to see if any other issues

Tx include

  • identification of underlying cause
  • topical anaesthetics e.g. lidocaine mouthwash
  • OTC meds such as ibuprofen
  • avoidance of triggers
  • hydration
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11
Q

When should / shouldn’t swellings be referred

A

Refer if
- symptomatic - pain is feature of salivary gland malignancy

  • abnormal overlying and surrounding mucosa
  • increase in size
  • rubbery consistency
  • trauma from teeth
  • unsightly

Usually dont refer
- tori
- Small polyps
- mucoceles - unless they become fixed in size

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12
Q

Give some causes of oral white lesions?

A

Hereditary

Smoking / frictonal

Lichen planus

Candida leukoplakia

Carcinoma

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13
Q

Why are white lesions white?

A

Loss of blood circulation to the tissues - vasoconstriction

Thickening of mucosa or keratin - less visibility of the blood vessels through tissue

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14
Q

Define leukoplakia

A

A white patch which cannot be scraped off or attributed to any other cause

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15
Q

Diagnose, aetiology, symptoms and tx?

A

Fordyces spots

Ectopic sebaceous glands, benign, not any malignant potential

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16
Q

Diagnosis, cause? Symptoms and tx?

A

Frictional kerotosis

  • often a direct traumatic cause
  • often in those with parafunctional habits with buccinator contraction causing cheeks to rub against buccal cusps
17
Q

Diagnosis? Cause?

Symptoms? Tx?

A

White sponge Naevus

  • hereditary keratosis
  • obviously not trauma as teeth wont cause trauma right in sulcus
  • often starts in childhood and within families history

Monitor, refer for biopsy if spreading to other areas of body e.g. genitalia

caused by fluid filled areas between epithelial layers

18
Q

What features of white spots spark warning signs?

A

Reactionary border around the white lesion, indicating it is malignant

Mucosal changes to the type epithelium

19
Q

Diagnose these two cases and give causes?

A

Pseudomembranous acute candidosis - thrush

Denture associated chronic candidosis

20
Q

When refer a white lesion?

A

If red and white, concentrate on red part

If lesion is becoming raised and thickened

If lesion is ‘without cause’
- lateral tongue
- anterior FOM
- soft palate area

21
Q

Why are red lesions red?

A

Blood flow increases
- inflammation
- dysplasia

Reduced thickness of the epithelium

22
Q

What is erythroplakia?

A

Unexplained reddening change of the oral mucosa

Cannot be attributed to other causes

More of a concern for malignancy than Leukoplakia

23
Q

What may cause a dark red/blue lesion?

A

Dark - slow moving blood due to varicosities

Light blue - clear fluid such as saliva (mucocele) or lymph (lymphangioma)

24
Q

Give some possible causes of mucosal pigmentation

A

Exogenous staining of
- tea, coffee, smoking, chlorhexadine

Intrinsic pigmentation
- reactive Melanosis
- melanocytic naevus
- melanoma

Foreign body
- amalgam

25
Q

What presentation may addisons have?

A

Black pigmentation / staining due to raised ACTH levels - causing increased melanin production

26
Q

When refer mucosal pigmentation?

A

Is it easily explained?
- racial, smoking, medicines

Increasing in size, colour or quantity

New systemic problems?

27
Q

Characteristics of a melanoma?

A

Variable pigmentation

Irregular outline

Raised surface

Symptomatic
- itch
- bleed

28
Q

What are the uses for a biopsy? When must it be done?

A

Identify or exclude malignancy

Identify dysplasia which can be pre malignant

Identify pother disease e.g. lichen planus

Must be done if there is an unexplained, white, red or pigmented patch