indirect sympathomimetics Flashcards

1
Q

what are the indirect sympathomimetic drugs?

A

amphetamine-like
modafinil
armodafinil

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2
Q

what do indirect sympathomimetic drugs treat?

A

ADHD

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3
Q

what is the mechanism of indirect sympathomimetics?

A

compete with NET to prevent the reuptake of norepi thereby increasing the conc at the synaptic cleft

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4
Q

what are modafinil and armodafinil?

A

they’re amphetamine substitute with less side effects

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5
Q

clinical indication for modafinil and armodafinil?

A

narcolepsy - increase norepi to keep alert
adhd

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6
Q

what are the two catecholamine reuptake inhibitors?

A

atomoxetine
cocaine

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7
Q

mechanism of catecholamine reuptake inhibitors?

A

inhibits reuptake of norepi transporter NET

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8
Q

what kind of drug is cocaine?

A

a stimulant

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9
Q

what is the pharmacodynamic of atomoxetine?

A

increase norepi in the synapses

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10
Q

what is the pharmacodynamic of cocaine?

A

inhibit dopamine reuptake in the pleasure center of the brain which will increase the dopamine effect

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