connective tissue Flashcards

1
Q

3 elements of ct

A

cell
fiber
noncellular matrix material

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2
Q

classification of ct

A

embryonal and adult

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3
Q

2 types under embryonal ct

A

mucoid ct
mesenchymal ct

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4
Q

the unspecialized mesodermal tissue

A

mesenchymal ct

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5
Q

these ct are stellate or spindle shaped with cytoplasmic processes that eventually transform jnto various adult cell types

A

mesenchymal ct

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6
Q

a more advanced stage of mesenchymal ct

A

mucoid ct

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7
Q

mucoid ct is present in ____&

A

Wharton’s jelly of umbilical cord
comb and wattle of birds
lamina propium of omasum

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8
Q

principal component of mesenchymal ct

A

mesenchymal cells with insignificant amnt of intercellular substance and fluid

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9
Q

principal component of mucoid ct

A

intercellular substance( amorphous matrix and ground substance appears granular in proper fixation

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10
Q

fibril forming collagen

A

types 1,2,3, 5, 11

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11
Q

what type of collagen is predominate in ct

A

type 1

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12
Q

connect 1 tissue or organ to another

A

ct

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13
Q

minor component of mucoid ct

A

fine collagen and elastic fibers and cells and mesenchymal cells

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14
Q

prinicipal component of fibrous ct

A

fibers

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15
Q

fibrous ct is classified accdg to

A

fiber packing or density
fiber orientation or arrangement
fiber type

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16
Q

a type of fibrous ct where only the irregular form exists

A

loose

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17
Q

most common or ordinary ct in the body

A

loose

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18
Q

composed of loose array of randomly oriented collagenous, reticular and elastic fiber

A

loose

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19
Q

loose ct is found in

A

lamina popria
t. su mucosa of tubular organs
mesenteries
subcutis

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20
Q

it is where loose ct usually hypercellular and considered a diffuse lymphatic tissue

A

subcutis

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21
Q

principal component of loose ct

A

cells and intercellular substance

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22
Q

function of loose ct

A

strength, support, elasticity

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23
Q

2 classification of loos ct (cellular components)

A

resident and wandering cells

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24
Q

the normal constituents of ct and produced, grow old and die in the ct

A

resident cells of loose ct

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25
Q

what are the resident cells

A

fibroblast
mast cells
pericytes
fats
macrophages
mesenchymal cells
foreign body giant cells
reticular cells

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26
Q

derived from leukocytes themselves thay have invaded the loose ct when it is needed

A

transient or migrant cells

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27
Q

7 transient cells

A

plasma cells
pigment
lymphocytes
monocytes
neutrophils
eosinophils
basophils

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28
Q

the most numerous and important resident cells of loose ct

A

fibroblast

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29
Q

shape of fibroblast

A

between fiber- spindle shaped
not associated with fibers- stellate

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30
Q

what does the fibroblast secrete

A

collagen and elastic precursor

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31
Q

they form scar tissue when monocytes are destroyed

A

fibroblast

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32
Q

how does finroblast form scar tissue

A

secretes collagen fibers to fill the gaps left by dead myocyte

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33
Q

process kf scar formation

A

fibrosis

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34
Q

fibroblast in a quisxent phase is termed

A

fibrocytes

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35
Q

phase where fibroblasg is involved in fiber maintenance insted of fiber production

A

quisxent phase

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36
Q

small spindle shaped cells that usually lie between bundles of fibers

A

fibrocytes

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37
Q

oval cells with a small oval nucleus and coarse, basophilic cytoplasmic granules containing heparin and histamin and serotonind

A

mast cellss

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38
Q

a hofmone6that is anticoagulant

A

heparin

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39
Q

component of mast cells that increases vascular permeability and smooth muscle contraction

A

histamine

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40
Q

histiocytes or clasmatocytes

A

macrophages

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41
Q

very common phagocytic wandering cells in loose ct

A

macrophages

42
Q

deals with routine contaminants as well as to clean up debris hemorrhage and dead cells

A

macrophages

43
Q

specialized bacteria for phagocytosis

A

tubercle bacili

44
Q

large multinucleated cells formed from fusion of monocytes or macrophages

A

foreign body giant cells

45
Q

encloses foreign objects or debris that are too large or too resistant yo be engilfed and destroyed by single phagocyte

A

foreign body giant cells

46
Q

adipose cells occurs singly in ____

A

loose ct, inactive mammary gland, dermis and hypodermis and yellow bone marrow

47
Q

type kf fat cells that serve as a reserve store of energy and as a shock cushion for internal organs

A

white fat cells

48
Q

these fat cells are long lived and do not divide so its number is fixed throughout life

A

white fat cells

49
Q

multiocular with many small fat globules and a round nucleus with no specific position jn the cytoplasm

A

brown fat cells

50
Q

why is brown fat cells color brown

A

due to the numerous mitochondria that cast a brown color to the fresh specimen

51
Q

especially well developed in rodents that hibernate

A

brown fats

52
Q

it is a thermogenic tissue. which functions is to generate heat

A

brown fat

53
Q

found in the interscapular region of mammals and especially well developed in rats that hibernate

A

brown fat cells

54
Q

They are difficult to identify in tissue sections stained with H&E. They have stellate or spindle-shaped like the mesenchymal cells and therefore difficult to differentiate from the latter.

A

reticular cells

55
Q

formation of framework (stroma) of organs and binds together smooth muscle tissue cells.

A

reticular cells

56
Q

any cell type that occur around capillaries or small vessels where they intimately contact with the lining endothelium

A

pericyte

57
Q

are rare in loose connective tissues but if present, it could be fibroblast that have de-differentiated

A

mesenchymal cells

58
Q

activated B lymphocytes

A

plasma cells

59
Q

oval in shape with eccentrically placed nucleus.

A

plasma cells

60
Q

The nucleus presents a “clock face” appearance where the centrally located nucleolus is surrounded by clumps heterochromatin

A

plasma cells

61
Q

plasma cell in TEM

A

in its active state is packed with an extensive RER, accounting for the deep basophilia of the cell

62
Q

Principal producers of antibodies (immunoglobulins) that participate in the body’s humoral defense against infection

A

plasma cells

63
Q

pigment-containing cells of loose connective tissue

A

pigment cells or melanocytes

64
Q

pigmented loose ct where

A

core of iris, ciliary body, and ciliary process of eye

65
Q

Present in inflammatory sites, lymphatic organs, and in the lamina propria of the GUT wall together with numerous lymphocytes. Differentiate from circulating blood connective tissue (reversible process).

A

plasma cells

66
Q

principal component of dense connective tissue

A

fiber

67
Q

has a coarse network of collagen fibers (with a few elastic and reticular fibers) arranged at random.

A

irregular dense fibrous ct

68
Q

They have more fibers and fewer cells (fibroblast) than in loose connective tissue

A

irregular dfct

69
Q

irregular dfct is found in

A

reticular layer of the dermis of skin and capsule of organs.

70
Q

has numerous fibers run parallel to each other, an arrangement that confers tensile strength and stretch resistance.

A

regular dense fibrous ct

71
Q

have parallel bundles of collagen fibers between columns of fibroblast as principal component

A

dwfct/collagenous ct

72
Q

dwfct is founf in

A

tendons, most ligaments and aponeurosis

73
Q

have elastic fibers in parallel arrangement.

A

elastic ct

74
Q

provides springiness and stretchability to the tissues, like the nuchal ligament and the tunica media of large arterie

A

elastic fibers

75
Q

Sizeable defects in connective tissue are repaired by a combination of young fibroblast and capillary buds proliferating together to cover or fill in the defects. Such combination of fibroblasts and capillaries is called

A

granulation tissue

76
Q

color of granulation tissue

A

pink to red due to presence of numerous capillaries

77
Q

It forms the fibrous stroma of lymphatic and blood-forming organs, where some structural support is needed but collagen fibers are necessary

A

reticular ct

78
Q

principal component of reticular ct

A

fine reticular fibers arranged in network

79
Q

It acts like a basket that holds the cells, particularly the lymphocytes

A

reticular ct

80
Q

It is a loose connective tissue with pigmented-containing cells

A

pigmented ct

81
Q

pigmented ct is found in

A

iris, choroid and ciliary body and processes of the eye and in the connective tissue of pigmented skin

82
Q

Another variant of areolar connective tissue but its principal component is adipose cel

A

adipose tissue

83
Q

is widely distributed in the body and occurs in cluster and may be angular in shape due to pressure they exert on each other

A

white adipose tissue

84
Q

They have a characteristic “Chicken wire appearance”.

A

white adipose tissue

85
Q

can be found in hibernating rodents and in the intercapsular region of most young animals

A

vbrown adipose tissue

86
Q

is a variant of loose connective tissue but its principal component includes blood cells in various stages of development and maturation. It is further classified into myeloid and lymphatic tissues.

A

hematopoietic tissue

87
Q

produces majority of the blood cells.

A

myeloid tissue

88
Q

2 sources of myeloid tissue

A

red and yellow bone marrow

89
Q

have high cellular tissue blood cells in various stages of development, blood vessels and sinuses filled with erythrocytes.

A

red bone marrow

90
Q

Located in the intertrabecular or interosseous spaces of cancellous bone and marrow cavity of developing long bone

A

red bone marrow

91
Q

the cell easiest to identify in bone marrow

A

megakaryote

92
Q

Principal component are white adipose cells with developing cells as minor component

A

yellow bone marrow

93
Q

associated with bone trabeculae

A

yellow bone marrow

94
Q

produced lymphocytes. They are associated with the gastrointestinal and respiratory tracts are collectively called GALT

A

lymphatic tissue

95
Q

widely distributed in most ct and involved in allergic reaction

A

mast cells

96
Q

this is present in many organs like lung, liver, and digestive and lymphatic organs

A

macrophages

97
Q

pleiomorphic which means that their appearance varies with physiological state and activity

A

macrophages

98
Q

have angular contour and bean shaped nucleus

A

macrophages

99
Q

derived from circulating blood monocytes that migrate to ct

A

macrophages

100
Q

cells are contractile having control on the size of the vascular lumen

A

pericyte

101
Q
A