Endocrine Physiology ML:4 Flashcards

1
Q

What is the functional unit of the thyroid gland?

A

follicles

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2
Q

How are thyroid hormones stored?

A

They are really hydrophobic so they can be bound to thyroglobulin which is a protein that is stored in the colloid

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3
Q

True or False: The thyriod hormone is stored in the colloid fluid until it is stimulated to be secreted

A

true

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4
Q

How are thyroid hormones transferred to the blood?

A

by protein carriers

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5
Q

TBG protein carrier

A

70%

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6
Q

TTR protein carrier

A

10-15%

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7
Q

Albumin protein carrier

A

15-20%

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8
Q

What kind of hormone is a thyroid hormone

A

hydrophobic amine hormone
-binds to receptors inside the target cell

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9
Q

Characteristics of T4

A

90% of secretion
“storage pool” in blood
converted to T3 inside target cells

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10
Q

Characteristics of T3

A

most active form (bound to receptors in target cells)

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11
Q

Three gland cascade: thyroid gland

A

-hypothalamus secretes TRH
-anterior pituitary secretes TSH
Thyroid gland secretes T3 and T4

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12
Q

What are the three actions of the thyroid hormone?

A

metabolic
permissive
growth and development

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13
Q

Metabolic actions

A

controls BMR and body temp mainly by increasing sodium and potassium

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14
Q

Permissive actions

A

increases catecholamine expression

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15
Q

Growth and development

A

TH is needed for normal production of growth hormone (GH) and essential for fetal CNS development and function and adult nervous system function

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16
Q

Follicles trap what in order to produce thyroid hormones

A

iodine