IN CLASS MUSCLE PHYS Flashcards

1
Q

Three sources of ATP for muscle contraction

A

-phosphorylation of ATP for muscle contraction
-OP of ADP in mito
-Phosphorylation of ADP by glycolysis in cytosol

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2
Q

Time stamps for OP of ADP

A

5-10: draws nutrients from muscle glycogen
30 min: blood glucose and fatty acids
>30: blood fatty acids dominate

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3
Q

SO
rate of fatigue, rate of contraction, recover time

A

slow, slow, slow

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4
Q

SO
type of movement, motor neuron size, myglobin

A

low and long intensity, smallest, high (red color)

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5
Q

FOG
myoglobin, contraction velocity, fatigue

A

high (red color), fast, more resistant

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6
Q

FOG
type of movement, recovery time

A

aerobic/endurance activities, faster

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7
Q

FG
fatigue, type of movement, recovery time

A

least resistant to fatigue, powerlifting/soritning, fast

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8
Q

FG
motor neuron, myoglobin

A

largest motor neuron, no myoglobin (white )

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9
Q

What does the duration of contraction depend on?

A

the time cytosolic calcium remains elevated allowing the XBs to continue to cycle

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10
Q

What is muscle fatigue?

A

tension decreases even though stimulation occurs

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11
Q

What causes skeletal muscle fatigue?

A

-decrease in ATP production
-cell can no longer complete XB cycle
-build up of metabolites
-Mass action effect of ADP and Pi

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12
Q

Build up of metabolites

A

Aerobic: CO2 H2O
Anaerobic: lactic acid
MG and H decrease RYR calcium release, reuptake storage by SR and decrease calcium sensitivity of thin filament proteins

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13
Q

Mass action of ADP and Pi

A

these two things directly inhibit the power stroke motion of the myosin cross bridge, decreasing shortening velocity and impairs relaxation

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14
Q

What causes mass action effect

A

ADP and Pi build up because ATP is used to move the XV and you are burning alot of ATP
-when there is buildup more ATP will not be hydrolyzed leading to it

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