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IMMUNE1 LAB MIDTERM AND FINALS > POST LAB EXPERIMENT 9 > Flashcards

POST LAB EXPERIMENT 9 Flashcards

1
Q

Primary defenses against treponemal invasion are

A

intact skin and mucous membranes

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2
Q

Skin is penetrated- (?) play a key role in
the immune response

A

T cells and macrophages

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3
Q

Reported in Medical Literature as early as

A

1495

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4
Q

-discovered that syphilis was caused by a spirochete bacteria Treponema pallidum

A

1905

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5
Q

Causative agent:

A

Treponema pallidum subspecies pallidum

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6
Q

Primary mode of infection:

A

Sexual transmission

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7
Q

Other modes:

A

Congenital infection, Parenteral exposure

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8
Q

10 to 90 days after infection

A

Primary Stage Syphilis

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9
Q

Chancre

A

Primary Stage Syphilis

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10
Q

painless, solitary lesion characterized by raised well defined borders

A

Chancre

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11
Q

a painless chancre develops at the site where the bacteria entered the body.

A

Primary Stage Syphilis

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12
Q

A person is highly contagious during the

A

Primary Stage Syphilis

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13
Q

The chancre lasts (?) and heals without treatment

A

28-42 days

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14
Q

Systemic dissemination of organisms occurs

A

Secondary Syphilis

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15
Q

Secondary Syphilis

Observed (?) after primary chancre

A

1 to 2 months

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16
Q

Generalized lymphadenopathy

A

Secondary Syphilis

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17
Q

A rash often develops all over the body, including palms of the hands and the soles of the feet

A

Condylomata lata

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18
Q

The rash usually heals without scarring in

A

2-12 wk.

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19
Q

Open sores may be present on mucous membranes and may contain pus flat lesions resembling warts in moist areas of the body (e.g., around the anus or vagina)

A

Condylomata lata

20
Q

These lesions do not reflect areas of inoculation but appear to be caused by hematogenous dissemination of spirochetes.

A

Condylomata lata

21
Q

Symptoms can include nervous system abnormalities.

A

Secondary Syphilis

22
Q

Disappearance of secondary syphilis

A

Latent stage Syphilis

23
Q

Stage that lacks clinical symptom

A

Latent stage Syphilis

24
Q

: less than 1 year duration

A

Early latent stage

25
Q

: More than 1 year of infection

A

Late latent stage

26
Q

If untreated, an infected person will progress to the (hidden) stage of syphilis with no symptoms

A

Latent stage Syphilis

27
Q

The latent period may be as brief as (?) or range from (?)

A

1 yr

5-20 yr.

28
Q

A person is contagious during the early part of the latent stage and may be contagious during the latent period.

A

Latent stage Syphilis

29
Q

Gummas

A

Late (Tertiary) stage syphilis

30
Q

– localized areas of granulomatous inflammation

A

Gummas

31
Q

Bones, skin and subcutaneous tissue

A

Gummas

32
Q

May heal with scarring or remain destructive areas of chronic inflammation

A

Late (Tertiary) stage syphilis

33
Q

Most destructive stage of syphilis

A

Late (Tertiary) stage syphilis

34
Q

If untreated, the tertiary stage may begin as early as 1 yr
after infection or at any time during a person’s lifetime.

A

Late (Tertiary) stage syphilis

35
Q

A person may never experience this stage of the illness.

A

Late (Tertiary) stage syphilis

36
Q

symptoms depend on the complications that develop—gummata

A

Late (Tertiary) stage syphilis

37
Q

large sores inside the body or on the skin, cardiovascular syphilis, or neurosyphilis.

A

gummata

38
Q

Degeneration of the lower spinal cord

A

Tabes Dorsalis

39
Q

General paresis

A

Tabes Dorsalis

40
Q

Chronic progressive dementia

A

Tabes Dorsalis

41
Q

Seen in immunodeficient patients

A

Neurosyphilis

42
Q

May occur any time after primary stage

A

Neurosyphilis

43
Q

malaise

A

Secondary Syphilis

44
Q

fever

A

Secondary Syphilis

45
Q

pharyngitis

A

Secondary Syphilis

46
Q

rash in the skin and mucous membranes

A

Secondary Syphilis

47
Q

Condylomata lata

A

Secondary Syphilis

IMMUNE1 LAB MIDTERM AND FINALS (16 decks)

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