Module 5 Flashcards

1
Q

What gives someone a bitter taste gene?

A

PCT

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2
Q

Is PCT dominant or recessive?

A

Dominant

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3
Q

What is sickle cell anaemia?

A

Red blood cells that cannot carry oxygen

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4
Q

P+q=?

A

1

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5
Q

What is the assumptions of Hardy -Weinberg principle?

A

Random mating, reaches equilibrium etc

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6
Q

X2=sum(obs-exp)^2/exp

A
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7
Q

What is the equation for Hardy -Weinberg principle?

A

p^2 +2qp +q^2=1

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8
Q

What happens when non-random mating occurs?

A

Excess homozygous indivudals

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9
Q

What is fitness?

A

The ability to survive and produce (utilise resources, fitness through geneotype or phenotype)

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10
Q

How fitness synbalized?

A

W,
0=dies
1=1offspring etc

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11
Q

What is a growing population?

A

W>1

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12
Q

What is a stable population?

A

W=1

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13
Q

What is a declining population?

A

W<1

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14
Q

What does s measure?

A

selection coefficient?

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15
Q

What is directional selection?

A

Peak is moved left or right

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16
Q

What is disruptive selection?

A

Min peak where max peak

17
Q

What is stabilising selection?

A

Peak is pinched in

18
Q

How is more likely to be carries of sickle cell anaemia?

A

Heterozygous individuals (carries)

19
Q

Balanced polymorphism?

A

p=t/(s+t)

20
Q

How is mutation selection balanced reached equiblium?

A

elimination of deleterious alleles is = to new mutations

21
Q

Does mutation increase or decrease heterozygosity?

A

Increase

22
Q

Does drift increase or decrease heterozygosity?

A

Decrease

23
Q

What is a non-synonymous mutation?

A

Changes amino acid

24
Q

What is a synonymous mutation?

A

does not change an amino acid

25
Q

Chromosomes are mosaics, what does this mean?

A

they depend on recombination, mutation, population and slection rates and time

26
Q

In large population, new mutations are more likely to be neutral to the population, why is this?

A

More genetic variability in the population

27
Q

What test for you use for neutrality?

A

Tajam’s D

28
Q

Why are neutrality test important?

A

to make assumptions about the demography populations

29
Q

How to determine species?

A

Cytogenetics

30
Q

How does cytogenetics work?

A

Polytene chromosomes

31
Q

How is nuclear DNA inherited?

A

Population size = 4Ne

32
Q

How is Mitochondrial DNA inherited?

A

single lineage, Ne

33
Q
A