Module 6 Flashcards
What is translocation?
Swap of nucleotide on each strand
What is huntington’s disease?
Autosomal dominant disorder on chromosome 4, repeated trinucleotide
In a human pedigreee tree, how do we tell if someone is dominant or recessive?
Recessive has no parental trait whereas dominant does.
What is cystic fibrosis?
Autosomal recessive
What are multifactorial genetic diseases?
Consequences of variations of mutations in maple genes
What can contribute to environment for mutations?
Parenting, culture, smoking, drinking etc.
What is hemochromatosis?
The body absorbs too much iron from food, inherited but small number have serious problems
What is aneuploidy?
Having an unusually amount of chromosomes
What chromsomes does\ down syndrome affect?
16 to 17
What does non-disjunction mean?
Failure to separate, e.g chromosomes
What is germline mutations?
Every cell in body
What are somatic mutations?
only daughter cells
What is anuegen?
Changes number of chromosomes
What is teratofen?
Causes malformation of an embryo
What is tumour supressor genes?
when mutated fail to supress pathways which lead to cancer
