biological area year 2 Flashcards

1
Q

what is brain plasticity?

A

the ability of the brain to modify its own structure and function

refers to the brain’s ability to recognise neural pathways throughout the lifespan as a result of experience

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2
Q

aim of blakemore and cooper?

A

to limit the visual experience of kittens to one orientation and to compare the behavioural consequences of this restricted visual environment on the kittens

to investigate the neuropsychological effects on the neurones in the kittens’ visual cortex

to investigate the responses of the kittens’ brain development to their environment and illustrate brain plasticity in their developing visual sense

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3
Q

sample of blakemore and cooper?

A

kittens, from birth to approximately one year old

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4
Q

procedure of blakemore and cooper?

A

from birth, kittens were housed in a completely dark room

from 2 weeks, the kittens were placed into a specially designed cylindrical apparatus, which was 46cm in diameter and 2m high

the cylinder was decorated with either vertical or horizontal stripes (the two conditions)

the stripes were black and white, high contrast and a variety of widths

the kittens were allocated to one of the two conditions and were placed in the cylinder for five hours a day

the kittens also wore a wide collar so they could not see their own bodies, which also limited their vision to about 130 degrees

a top cover/lid was placed on the cylinder whilst they were in there

the cats’ behaviour and brain neural patterns (in 2 anesthetised cats) were measured

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5
Q

what were the behavioural findings in blakemore and cooper?

A

the kittens often bumped into things

horizontally reared kittens would only respond to a rod being shaken at them if it was shaken horizontally and not vertically

showed no startle responses when an object or hand was thrust in front of them

their visual placing was impacted: they did not stretch their paws out when they were held out to be put down on a table. They only did when they felt the table

these effects seem to disappear after 10 hours in the well lit room but their tracking of moving objects remained jerky and they were still clumsy.

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6
Q

what were the neurological (brain) results of blakemore and cooper?

A

2 of the kittens were anaesthetised (with their eyes open) and had an electrode an inserted into their visual cortex to measure neural activity. One kitten had been reared in a vertical environment, the other horizontal

a normal cat’s pattern of neurons would have a balance of horizontal and vertical patterns

they found that kittens appeared to suffer from ‘physical blindness;

they found the kittens would show patterns of neurons in the same orientation as their reared environment

they showed little activity when shown images opposite to their original environment

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7
Q

conclusions of blakemore and cooper?

A

early visual experiences can modify a kitten’s perception in term of their behaviour and biology

the brain can change as a result of experience (plasticity)

brain development can be affected nurture

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8
Q

what is the hippocampus?

A

bilateral brain structure (we have a left and right hippocampus)

role is memory and spatial navigation

right is predominantly for spatial navigation

left is for episodic memories

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9
Q

what is the anterior hippocampus?

A

the front of the hippocampus

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10
Q

what is the posterior hippocampus?

A

the back of the hippocampus

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11
Q

what is white matter?

A

axons that connect the grey matter

makes up 60% of the brain

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12
Q

what is grey matter

A

the cell bodies

lies on the surface of the brain

makes up 40% of the brain

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13
Q

What is The Knowledge?

A

a test that all London cab drivers need to pass

need to know 25,000 streets and 20,000 landmarks

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13
Q

what was the aim of Maguire?

A

to investigate whether experience does actually change the structures of the brain

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14
Q

who were the ps in the experimental condition in maguire?

A

16 male London taxi drivers

32-62 years

right handed

had been licenced for more than 1.5 years

average time spent training on the Knowledge test was 2 years

healthy general medical, neurological and psychiatric profiles

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15
Q

who were the ps in the control group in maguire?

A

non taxi drivers’ scans were selected from the structural MRI scan database at the same unit where the taxi drivers were scanned

50 in total (males)

age range 32 - 62 years (same as experimental conditions)

right handed

no health problems

16
Q

procedure of Maguire?

A

Participants had MRI scans. A blind experimenter then analysed the MRI results (they did not know which scan was a taxi driver’s and which was a non taxi driver’s scan when analysing

17
Q

what were the techniques used to analyse the brain scans in maguire?

A

VBM - Voxel-Based Morphometry

Pixel Counting

18
Q

what is VBM ( Voxel Based Morphometry )?

A

a technique that measures the density of grey matter

19
Q

what is pixel counting?

A

a technique that analyses ‘slices’ of the scan (24 slices of the hippocampus) to calculate volume

20
Q

what were the VBM results in maguire?

A

taxi drivers had more grey matter in their posterior hippocampi

non-taxi drivers had more grey matter in their anterior

21
Q

what were the pixel counting results in Maguire?

A

no difference between taxi drivers and non taxi drivers overall volume of their hippocampi

non taxi drivers had more hippocampal volume in their anterior

taxi drivers had more volume in their posterior

22
Q

what were the correlational results in maguire?

A

a correlation was conduced to see if there was a relationship between time spent as a taxi driver (including time learning The Knowledge) in months, and the hippocampal volume

it was found that there was a positive correlation between time spent as a taxi driver and the right posterior hippocampus

there was therefore a negative correlation between time spent as a taxi driver and the volume of the right anterior hippocampus