DIPTHERIA Flashcards
Diphtheria: Prevention of Secondary Cases
Q: What is the goal of antibacterial prophylaxis in diphtheria?
A: To reduce the risk of secondary disease by treating incubating disease in recently exposed contacts and eliminating asymptomatic carriage of diphtheria.
Q: Who leads the management of close contacts of confirmed or probable diphtheria cases or asymptomatic carriers?
A: Local health protection teams.
Q: When should close contacts of a confirmed or probable diphtheria case or asymptomatic carrier be given antibacterial prophylaxis?
A: They should be investigated immediately, kept under surveillance, and given antibacterial prophylaxis.
Q: In which settings should antibacterial prophylaxis be offered to individuals who have contact with a diphtheria case or known carrier?
A: In household settings, for those with transient close contact, particularly if they have been directly exposed to large particle droplets or secretions (e.g., kissing or sexual contacts), or if they have been exposed to an undressed wound of a cutaneous case (e.g., healthcare workers).
Q: What additional measure should be considered alongside antibacterial prophylaxis following contact with a diphtheria case or carrier?
A: Vaccination with a diphtheria-containing vaccine.
Q: What are the first-line choices for antibacterial prophylaxis in diphtheria?
A:** Azithromycin or clarithromycin**.
Q: What is the alternative choice for antibacterial prophylaxis if it needs to be more easily administered?
A: Benzathine benzylpenicillin.
Diphtheria: Prevention of Secondary Cases
Q: What is the goal of antibacterial prophylaxis in diphtheria?
A: To reduce the risk of secondary disease by treating incubating disease in recently exposed contacts and eliminating asymptomatic carriage of diphtheria.
Q: Who leads the management of close contacts of confirmed or probable diphtheria cases or asymptomatic carriers?
A: Local health protection teams.
Q: When should close contacts of a confirmed or probable diphtheria case or asymptomatic carrier be given antibacterial prophylaxis?
A: They should be investigated immediately, kept under surveillance, and given antibacterial prophylaxis.
Q: In which settings should antibacterial prophylaxis be offered to individuals who have contact with a diphtheria case or known carrier?
A: In household settings, for those with transient close contact, particularly if they have been directly exposed to large particle droplets or secretions (e.g., kissing or sexual contacts), or if they have been exposed to an undressed wound of a cutaneous case (e.g., healthcare workers).
Q: What additional measure should be considered alongside antibacterial prophylaxis following contact with a diphtheria case or carrier?
A: Vaccination with a diphtheria-containing vaccine.
Q: What are the first-line choices for antibacterial prophylaxis in diphtheria?
A: Azithromycin or clarithromycin.
Q: What is the alternative choice for antibacterial prophylaxis if it needs to be more easily administered?
A: Benzathine benzylpenicillin.
These flashcards can help you remember the key points for preventing secondary cases in diphtheria.
DP-MAC
Diptheria/pertussis prohylaxis is
MACROLIDE
