The Synthesis And Transport Of Proteins- The Secretory Pathway Flashcards
1
Q
Where are secreted proteins translated and where do they then enter?
A
They are translated in ribosomes on RER and enter its lumen
2
Q
What are examples of secretory proteins?
A
Peptide hormones and digestive enzymes
3
Q
What happens to secretory proteins after they move through the Golgi apparatus?
A
They are packaged into secretory vesicles which move to and fuse with the plasma membrane releasing the proteins out of the cell
4
Q
Many secretory proteins are synthesised as inactive precursors how do they become active?
A
They go through proteolytic cleavage to produce active proteins
5
Q
What is proteolytic cleavage?
A
Another type of post-translational modification
6
Q
What is an example of secretory protein that requires proteolytic cleavage to become active?
A
Digestive enzymes
