week 10 - metabolic bone disease

Question 1

generalised osteopenia

Answer 1

decreased bone density or increased radiolucency of done
- OP occurs when bone reabsorption exceeds bone formation
- leads to deective bone quality and strenght

Question 2

Osteoprosis

Answer 2

amount of bone present per unit of volume is reduced but the composition is normal
- characterised by progressive loss of bone mass, due to increased resorption as well as decreased bone production

Question 3

osteoprosis radiographic features

Answer 3

prominent primary trabeculations
thinning of the cortices
tunneling

Question 4

regional osteoporosis

Answer 4

affected 1 extremity

Question 5

osteomalacia

Answer 5

“softness of bone” - disorder with excessive amounts of uncalcified osteoid
- radiogrpahic features non-specific, consisting primarily of osteopenia

Question 6

hperparathyroidism

Answer 6

increased levels of parathyroid hormone which indirectly leads to increased osteoclastic activity and removal of calcium from bone that enters the blood

Question 7

Rickets

Answer 7

disease of growing bone that is unique to children and adolescents - failure of osteoid to calcify in a growing person

Question 8

acromegaly

Answer 8

osteoblast proliferation is regulated by HG and insulin like growth factor type I

Question 9

osteogenesis imperfecta

Answer 9

hetergeneous group of inherited disorders characterised by an involvement of bones and extraskeletal tissues

Question 10

paget disease

Answer 10

• second most common aging bone disorder, excessive and abnormal remodeling of bone