Structural Aberrations: Duplications

Question 1

In this chromosomal aberration, an additional copy of a segment of a chromo- some is present.

Answer 1

Duplications

Question 2

Duplications may originate from ____?

Answer 2

Unequal crossing over
Meiotic events in a parent with a translocation, inversion, and isochromosome.

Question 3

T/F. Duplications are more common than deletions and are generally less harmful. Indeed, tiny duplications at the molecular level (repeats) may play an important role in permitting gene diversification during evolution.

Answer 3

True.