Neurotransmission

Question 1

what is the propagation of a current

Answer 1

a process where the changing potential is passed along the neuron
in unmyelinated axons this is a slow process with a high energy requirement

Question 2

what does myelination do

Answer 2

speeds up the propagation by facilitating saltatory conduction
this is where action potentials are only generated at gaps in the myelin

Question 3

what are nodes of Ranvier

Answer 3

gaps in the myelin sheath where action potentials are generated

Question 4

what does demyelination cause

Answer 4

poor insulation and inefficient conduction
impairs the axon health as metabolic support is lost

Question 5

what can drug overdose lead to

Answer 5

disruption of the fine balance between excitation and inhibition
can lead to lethargy, slurred speech, poor coordination, bradycardia, hypotension, apnoea