ch 12 Flashcards

1
Q

what is DNA polymorphism?

A

sequences differences - serves as DNA markers

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2
Q

what are the three types of genetic variants?

A

SNP - single nuc
DIP deletion insertion
SSR simple sequence repear

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3
Q

what can SNP let you do in relation to ancestry?

A

trace it since you share more with closer relatives

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4
Q

what can DIPS lead to?

A

frame shift mutations within exons

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5
Q

what is PCR? what can you make?

A

a way to isolate a fragment of DNA for anaylsis
-primers (1 in 3 to 5 and the other 5 to 3 convert the parent to complementary and convert that )

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6
Q

if your given a cahrt with the locus, genotype, and match probaility with the amount of people in the population how can you solve this?

A

To tell how many have the same profiles multiply all of the match probabilities into decimals and multiply it to how ever many people there are

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7
Q

What happens when the oligonucleotides is not an exact match?

A

then hybridization is less stable making it easier to denature at a lower temperature

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8
Q

allele-specific oligonucleotides (ASOS)

A

only hybridize to one of the two alleles at a SNP location

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9
Q

SNP pedigrees can tell you ? and the one weird kid?

A

which letter causes the issue
- happened because of crossing over

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