STI Part 2

Question 1

Syphilis transmissibility

Answer 1

highly transmissible through kissing, lesions ever when asym

Question 2

Syphilis - sys or localized disease

Answer 2

sys

Question 3

Stages of syphilis

Answer 3

primary (asym or chancre) - secondary - latent (asym) (if less then 2 year resoltuion, if more then 2 year can become tertiary or have resolution)

Question 4

Syphilis and pregnancy

Answer 4

pregenancy can be asym or congenitial infection of ababy

Question 5

characterist of primary syphilis

Answer 5

chancre, lesion

Question 6

charcter of secondary syphilis

Answer 6

rash , fever, malaire , haedches, uveitus and retinitis

Question 7

charcteristics of latent syphilis

Answer 7

early ( infectious)
late (non infectious

• we tell via seroly and are poistive for life

Question 8

characteristics of tertiary syphilis

Answer 8

• cardiovascular syphilis
• neurosyphilis
  -gumma ( destruction of any organ)

Question 9

neurosyphilis features

Answer 9

sym or asym

• vertigo, headaches, loss of hearing(can be permanent), personality cahnges, dementia and ataxia

Question 10

what seroly marker are we looking for syphilis

Answer 10

• treponemal tests (positive for life)
  however goes down in volume as resolution of condition
• also look at reducing RPR or VDRL titres

Question 11

syphilis testing what to keep in mind

Answer 11

false negatives are common in primary so retets in 2-4 weeks if suspected or suspious case

Question 12

syphilis successful treament mean what lab value wise?

Answer 12

RpR and VDRL titre go down

Question 13

when is a lumbar indicated in syphilis

Answer 13

1. ocular syphilis
2. neurosyphilis
3. congenital syphilis
4. tx failure

Question 14

syphilis Tx for primary, secondary or early latent

and prego!

Answer 14

benzathine penicillin G IM - single dose

1-2 weekly doses recom

Question 15

syphilis tc for latent, tertiary not neuro

Answer 15

benzathine penicillin G IM weekly for 3 weeks

Question 16

syphilis tx for neurosyphilis

Answer 16

Penicillin G IV q 4h for 10-14 days (in hospital)

Question 17

syphilis follow up

Answer 17

primary or secondary: 1, 3, 6, 12 post tx
latent and tertiary: 12 and 24 months post tx

Question 18

syphilis serologic repsonse

Answer 18

primary
4 fold at 6 months
8 fold at 12 month
16 fold at 24 months

secondray
8 fold at 6 month
16 fold at 12 month

tertiary
4 fold at 12

Question 19

HPV how cmmon

Answer 19

most common STI

Question 20

HPV high risk

Answer 20

types 16 and 18 cause cervical anogenitla and some head and anck cancers

Question 21

HPV low risk types and effect

Answer 21

warts - usualy 6 and 11

Question 22

HPV transmissioon

Answer 22

skin to skin

Question 23

How do we prevent HPV

Answer 23

• condom
• pap smears
• HPV vax

Question 24

HPV vax

Answer 24

cervarix (HPV2)
gardasil (HPV9)

Question 25

cervarix (HPV 2) portects agaisnt

Answer 25

types 16 and 18

Question 26

gardasil 9 (HPV9) portects against

Answer 26

a bunch of types

Question 27

what does immunization do?

Answer 27

protect against cancer and warts

Question 28

vax schdule: girls 9-14

Answer 28

cervarix or gardasil
- 2 or 3 doses

Question 29

vax schdule: women and girlks over 15

Answer 29

cervarix or gardasil
- 3 doses

Question 30

Vax schdule: boys 9-14

Answer 30

gardenasil
- 2 or 3 doses

Question 31

Vax schdule: boys 15 plus, and men

Answer 31

gardensail
- 3 doses

Question 32

Anogenital warts caharcterist

Answer 32

can be asym, can cause bleeding, internal or external, self limiting, reoocurance is common

Question 33

anogenital warts tx self applied or clinician applied?

Answer 33

self - if extrnal
clincicain if external or prego

Question 34

anogenital warts topcial creasm

Answer 34

imiquimod
podophyllitoin
sinecatechins

Question 35

anaogenital cream to use cautiously in immuncomprised (immune rsponse modulator)

Answer 35

imiquimod

Question 36

whihc topical can you leave on and not have to wash off

Answer 36

podophyllitoin
sinecatechins