Atherosclerosis and coronary artery disease Flashcards

1
Q

what is atherosclerosis

A

arterial disease characterized by thickening and loss of flexibility

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2
Q

atherosclerosis plaques

A

atheromatous
ulcerated

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3
Q

atheromatous plaque

A

white/yellow
elevated from intima vessel

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4
Q

ulcerated plaque

A

red-brown color
due to thrombus accumulation

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5
Q

modifiable risk factors of atherosclerosis

A

hyperlipidemia,
hypertension
smoking
diabetes mellitus

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6
Q

additional risk factors of atherosclerosis include

A

inflammation
metabolic syndrome
factors affecting hemostasis
lack of exercise
stress
obesity

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7
Q

non modifiable atherosclerosis factors

A

age
gender
genetics

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8
Q

diagnosis of atherosclerosis

A

angiography
doppler ultrasound

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9
Q

results of atherosclerosis

A

**severely narrow or completely block of artery
**M.I or stroke

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10
Q

clinical consequences of atherosclerosis include

A

**plaque rupture and erosion
**thrombus formation
**vasoconstriction
**aneurysm

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11
Q

Coronary artery disease

A

progressive disease that occur with a decrease in coronary blood flow at rest or during exertion.

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12
Q

controllable risk factors for coronary artery disease

A

**high cholesterol
**diabetes
**high blood pressure
**smoking
**obesity

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13
Q

uncontrollable risk factors for coronary artery disease

A

menopause
age
family history of CAD
male gender

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14
Q

diagnosis of CAD

A

first step tests
invasive tests

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15
Q

first step tests

A

**biochemical laboratory test
**electrocardiography and ambulatory monitoring
**Endocardiography

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16
Q

invasive test

A

interventional coronary angiography only when noninvasive are inconclusive.

17
Q

treatments

A

*Lifestyle management
*Revascularization surgeries
**Percutaneous coronary intervention [PCI]
**Coronary artery bypass graft [CABG]

18
Q

PCI

A

minimally invasive
improve blood flow
include balloon angioplasty and intracoronary stent

19
Q

CABG

A

**one or more graft bridge
**saphenous vein most preferred vein graft
**internal thoracic and radial arteries are preferred arterial graft

20
Q

cardiac rehabilitation

A

has three phases
**perioperative phase
**outpatient phase
**post rehabilitation maintenance phase

21
Q

Laboratory tests

A

Complete blood count
Fasting glucose level
Thyroid hormones
Creatine level

22
Q

Sign of ischemia

A

Ecg ST segment depression